Jordi. Valles-Ortega, et.al., Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease., EMBO molecular medicine, 2011, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/21882344

Jordi. Valles-Ortega, et.al., Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease., EMBO molecular medicine, 2011, 3

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron morphology_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002882IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• gliosis_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002183IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• hippocampal neuron degeneration_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0000811IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• decreased anxiety-related response_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0001364IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• Lafora bodies_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0014063IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• enhanced long term potentiation_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0003008IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• increased skeletal muscle glycogen level_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0010401IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• hyperactivity_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0001399IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• increased susceptibility to pharmacologically induced seizures_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002906IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• abnormal astrocyte morphology_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002182IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• abnormal brain morphology_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002152IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• abnormal glial cell morphology_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0003634IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg
• abnormal excitatory postsynaptic potential_Nhlrc1<tm1(KOMP)Vlcg>/Nhlrc1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002912IC57BL6JC57BL6NTacNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcgNhlrc1tm1KOMPVlcg