Michiko. Itoh, et.al., Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis., The American journal of pathology, 2011, 179

http://rdf.ncbi.nlm.nih.gov/pubmed/21906580

Michiko. Itoh, et.al., Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis., The American journal of pathology, 2011, 179

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating leptin level_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0005669I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• obese_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0001261I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased circulating interleukin-6 level_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0008596I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• adipose tissue inflammation_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0020386I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased susceptibility to weight gain_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0005455I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• decreased adiponectin level_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0004893I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• liver fibrosis_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0003333I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased circulating alanine transaminase level_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0002941I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased liver weight_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0002981I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased susceptibility to diet-induced obesity_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0005658I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased total body fat amount_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0010024I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased liver triglyceride level_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0009355I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• liver inflammation_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0001860I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• hepatic steatosis_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0002628I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased hepatocellular carcinoma incidence_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0003331I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased circulating free fatty acid level_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0001554I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl