Junko. Odajima, et.al., Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation., Developmental cell, 2011, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/21944720

Junko. Odajima, et.al., Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation., Developmental cell, 2011, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ccne1<tm2.1Pisc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304316
• Ccne1<tm3.1Pisc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304324

class

http://purl.org/net/cito/citesAsAuthority

• Ccne1<tm2.1Pisc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304316
• Ccne1<tm3.1Pisc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304324

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal dendritic spine morphology_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009936I129S2SvPasC57BL6SJLCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscTgNescre1Kln0TgNescre1KlnCcne2tm1PiscCcne1tm31Pisc
• reduced NMDA-mediated synaptic currents_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001902I129S2SvPasC57BL6SJLCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscTgNescre1Kln0TgNescre1KlnCcne2tm1PiscCcne1tm31Pisc
• abnormal synapse morphology_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009538I129S2SvPasC57BL6SJLCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscTgNescre1Kln0TgNescre1KlnCcne2tm1PiscCcne1tm31Pisc
• abnormal dendritic spine morphology_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>
  http://metadb.riken.jp/0009936I129S2SvPasCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscCcne1tm31PiscCcne2tm1Pisc
• reduced long term potentiation_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001473I129S2SvPasC57BL6SJLCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscTgNescre1Kln0TgNescre1KlnCcne2tm1PiscCcne1tm31Pisc
• no abnormal phenotype detected_Ccne1<tm2.1Pisc>/Ccne1<tm2.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>
  http://metadb.riken.jp/0002169I129S2SvPas129S4SvJaeC57BL6Ccne1tm21PiscCcne1tm21PiscCcne2tm1PiscCcne2tm1PiscCcne1tm21PiscCcne2tm1Pisc
• abnormal excitatory postsynaptic currents_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002910I129S2SvPasC57BL6SJLCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscTgNescre1Kln0TgNescre1KlnCcne2tm1PiscCcne1tm31Pisc
• abnormal spatial learning_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001463I129S2SvPasC57BL6SJLCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscTgNescre1Kln0TgNescre1KlnCcne2tm1PiscCcne1tm31Pisc
• abnormal excitatory postsynaptic potential_Ccne1<tm3.1Pisc>/Ccne1<tm3.1Pisc>,Ccne2<tm1Pisc>/Ccne2<tm1Pisc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002912I129S2SvPasC57BL6SJLCcne1tm31PiscCcne1tm31PiscCcne2tm1PiscCcne2tm1PiscTgNescre1Kln0TgNescre1KlnCcne2tm1PiscCcne1tm31Pisc