Hongyu. Luo, et.al., Efnb1 and Efnb2 proteins regulate thymocyte development, peripheral T cell differentiation, and antiviral immune responses and are essential for interleukin-6 (IL-6) signaling., The Journal of biological chemistry, 2011, 286

http://rdf.ncbi.nlm.nih.gov/pubmed/21976681

Hongyu. Luo, et.al., Efnb1 and Efnb2 proteins regulate thymocyte development, peripheral T cell differentiation, and antiviral immune responses and are essential for interleukin-6 (IL-6) signaling., The Journal of biological chemistry, 2011, 286

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Efnb1<tm1.1Jwu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5302529
• Efnb2<tm1.1Jwu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5302530

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal bone marrow cell morphology/development_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0002398B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• abnormal T cell differentiation_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0002145B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• decreased DN4 thymocyte number_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0010136B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• decreased spleen weight_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0004953B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• thymus hypoplasia_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0001823B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• decreased CD4-positive, alpha beta T cell number_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0008075B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• small spleen_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0000692B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• increased length of allograft survival_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0004751B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• small thymus_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0000706B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• abnormal T-helper 17 cell differentiation_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0010221B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• increased thymocyte apoptosis_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0009541B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• increased susceptibility to viral infection_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0002418B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• abnormal T-helper 1 cell differentiation_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0008088B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• decreased CD8-positive, alpha-beta T cell number_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0008079B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• increased double-negative T cell number_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0005090B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• spleen hypoplasia_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0000694B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• increased DN3 thymocyte number_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0010133B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• decreased T cell number_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0005018B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• decreased double-positive T cell number_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0005092B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu
• decreased thymus weight_Efnb1<tm1.1Jwu>/Efnb1<tm1.1Jwu>,Efnb2<tm1.1Jwu>/Efnb2<tm1.1Jwu>,Tg(Lck-cre)I540Jxm/0
  http://metadb.riken.jp/0004956B6CgEfnb2tm11JwuEfnb1tm11JwuTgLckcreI540JxmEfnb1tm11JwuEfnb1tm11JwuEfnb2tm11JwuEfnb2tm11JwuTgLckcreI540Jxm0TgLckcreI540JxmEfnb1tm11JwuEfnb2tm11Jwu

class

http://purl.org/net/cito/citesAsAuthority

• Efnb1<tm1.1Jwu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5302529
• Efnb2<tm1.1Jwu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5302530