Karima. Begriche, et.al., Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis., The Journal of biological chemistry, 2011, 286

http://rdf.ncbi.nlm.nih.gov/pubmed/21984834

Karima. Begriche, et.al., Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis., The Journal of biological chemistry, 2011, 286

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mc3r<tm1Butl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5302394

class

http://purl.org/net/cito/citesAsAuthority

• Mc3r<tm1Butl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5302394

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased lean body mass_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003961B6CgMc3rtm1ButlTgNesCre1KlnMc3rtm1ButlMc3rtm1ButlTgNescre1Kln0Mc3rtm1ButlTgNescre1Kln
• increased circulating leptin level_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0005669B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• abnormal locomotor activation_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nr5a1-cre)2Lowl/0
  http://metadb.riken.jp/0003313IC57BL6JFVBNJMc3rtm1ButlMc3rtm1ButlTgNr5a1cre2Lowl0Mc3rtm1ButlTgNr5a1cre2Lowl
• hypoactivity_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0001402B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• decreased lean body mass_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0003961B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• abnormal energy homeostasis_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nr5a1-cre)2Lowl/0
  http://metadb.riken.jp/0005448IC57BL6JFVBNJMc3rtm1ButlMc3rtm1ButlTgNr5a1cre2Lowl0Mc3rtm1ButlTgNr5a1cre2Lowl
• increased susceptibility to diet-induced obesity_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005658B6CgMc3rtm1ButlTgNesCre1KlnMc3rtm1ButlMc3rtm1ButlTgNescre1Kln0Mc3rtm1ButlTgNescre1Kln
• decreased lean body mass_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nr5a1-cre)2Lowl/0
  http://metadb.riken.jp/0003961IC57BL6JFVBNJMc3rtm1ButlMc3rtm1ButlTgNr5a1cre2Lowl0Mc3rtm1ButlTgNr5a1cre2Lowl
• increased total body fat amount_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0010024B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• increased inflammatory response_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0001846B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• abnormal adipose tissue amount_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nr5a1-cre)2Lowl/0
  http://metadb.riken.jp/0005452IC57BL6JFVBNJMc3rtm1ButlMc3rtm1ButlTgNr5a1cre2Lowl0Mc3rtm1ButlTgNr5a1cre2Lowl
• abnormal circulating leptin level_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nr5a1-cre)2Lowl/0
  http://metadb.riken.jp/0005667IC57BL6JFVBNJMc3rtm1ButlMc3rtm1ButlTgNr5a1cre2Lowl0Mc3rtm1ButlTgNr5a1cre2Lowl
• abnormal locomotor activation_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0003313B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• decreased circulating triglyceride level_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nr5a1-cre)2Lowl/0
  http://metadb.riken.jp/0002644IC57BL6JFVBNJMc3rtm1ButlMc3rtm1ButlTgNr5a1cre2Lowl0Mc3rtm1ButlTgNr5a1cre2Lowl
• abnormal energy homeostasis_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0005448B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• increased susceptibility to diet-induced obesity_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0005658B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• decreased circulating triglyceride level_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0002644B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• increased circulating insulin level_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0002079B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl
• abnormal body fat mass_Mc3r<tm1Butl>/Mc3r<tm1Butl>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0012320B6CgMc3rtm1ButlTgNesCre1KlnMc3rtm1ButlMc3rtm1ButlTgNescre1Kln0Mc3rtm1ButlTgNescre1Kln
• decreased energy expenditure_Mc3r<tm1Butl>/Mc3r<tm1Butl>
  http://metadb.riken.jp/0004890B6CgMc3rtm1ButlMc3rtm1ButlMc3rtm1ButlMc3rtm1Butl