Suzanne A. Hartford, et.al., Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21987787

Suzanne A. Hartford, et.al., Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• spontaneous chromosome breakage_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0004029I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• decreased primordial germ cell number_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0008392I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• oligozoospermia_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0002687I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• small testis_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0001147I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• early cellular replicative senescence_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0008008I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• decreased embryo size_Mcm9/Asf1a<Gt(XE518)Byg>/Mcm9/Asf1a<Gt(XE518)Byg>
  http://metadb.riken.jp/0001698I129P2OlaHsdC3HeBFeJMcm9Asf1aGtXE518BygMcm9Asf1aGtXE518BygMcm9Asf1aGtXE518Byg
• increased hepatocellular carcinoma incidence_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0003331I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• abnormal seminiferous tubule morphology_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0002216I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• increased tumor incidence_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0002020I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• abnormal seminiferous tubule morphology_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0002216I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• ovary hyperplasia_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0001128I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• abnormal spermatogonia morphology_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0006378I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• abnormal female germ cell morphology_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0006361I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• abnormal spermatogonia morphology_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0006378I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• increased ovary tumor incidence_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0008000I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• increased tumor incidence_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0002020I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• increased tumor incidence_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0002020I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• embryonic growth arrest_Mcm9/Asf1a<Gt(XE518)Byg>/Mcm9/Asf1a<Gt(XE518)Byg>
  http://metadb.riken.jp/0001730I129P2OlaHsdC3HeBFeJMcm9Asf1aGtXE518BygMcm9Asf1aGtXE518BygMcm9Asf1aGtXE518Byg
• abnormal ovarian follicle number_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0008871I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• increased hepatocellular carcinoma incidence_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0003331I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• abnormal seminiferous tubule morphology_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0002216I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• arrest of male meiosis_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0008261I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• arrest of male meiosis_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0008261I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• small testis_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0001147I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• decreased male germ cell number_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0004901I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi
• oligozoospermia_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0002687I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• decreased male germ cell number_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0004901I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• abnormal ovary physiology_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0003507I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• abnormal definitive hematopoiesis_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0002123I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• decreased oocyte number_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0005431I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• female infertility_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0001926I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• small testis_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0001147I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• decreased male germ cell number_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0004901I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• embryonic lethality, complete penetrance_Asf1a<Gt(AL0673)Wtsi>/Asf1a<Gt(AL0673)Wtsi>
  http://metadb.riken.jp/0011092I129P2OlaHsdC3HeBFeJAsf1aGtAL0673WtsiAsf1aGtAL0673WtsiAsf1aGtAL0673Wtsi
• oligozoospermia_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0002687I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• increased ovary tumor incidence_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0008000I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• decreased primordial ovarian follicle number_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0011121I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• arrest of male meiosis_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0008261I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• abnormal cell cycle_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0003077I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• abnormal spermatogonia morphology_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0006378I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• increased hepatocellular carcinoma incidence_Mcm9<Gt(XG743)Byg>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0003331I129P2OlaHsdC3HeBFeJMcm9GtXG743BygMcm9GtXG743BygMcm9GtXG743Byg
• embryonic lethality, complete penetrance_Mcm9/Asf1a<Gt(XE518)Byg>/Mcm9/Asf1a<Gt(XE518)Byg>
  http://metadb.riken.jp/0011092I129P2OlaHsdC3HeBFeJMcm9Asf1aGtXE518BygMcm9Asf1aGtXE518BygMcm9Asf1aGtXE518Byg
• increased adenoma incidence_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(AW0655)Wtsi>
  http://metadb.riken.jp/0010383I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtAW0655WtsiMcm9GtAW0655Wtsi
• increased ovary tumor incidence_Mcm9<Gt(AW0655)Wtsi>/Mcm9<Gt(XG743)Byg>
  http://metadb.riken.jp/0008000I129P2OlaHsdC3HeBFeJMcm9GtAW0655WtsiMcm9GtXG743BygMcm9GtXG743BygMcm9GtAW0655Wtsi