Albert S. Jun, et.al., An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis., Human molecular genetics, 2012, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/22002996

Albert S. Jun, et.al., An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis., Human molecular genetics, 2012, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col8a2<tm1.1Asj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305275

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal endoplasmic reticulum morphology_Col8a2<tm1.1Asj>/Col8a2<tm1.1Asj>
  http://metadb.riken.jp/0009378I129S6SvEvTacC57BL6CBACol8a2tm11AsjCol8a2tm11AsjCol8a2tm11Asj
• increased apoptosis_Col8a2<tm1.1Asj>/Col8a2<tm1.1Asj>
  http://metadb.riken.jp/0006042I129S6SvEvTacC57BL6CBACol8a2tm11AsjCol8a2tm11AsjCol8a2tm11Asj
• abnormal corneal endothelium morphology_Col8a2<tm1.1Asj>/Col8a2<tm1.1Asj>
  http://metadb.riken.jp/0005301I129S6SvEvTacC57BL6CBACol8a2tm11AsjCol8a2tm11AsjCol8a2tm11Asj
• abnormal mitochondrion morphology_Col8a2<tm1.1Asj>/Col8a2<tm1.1Asj>
  http://metadb.riken.jp/0006035I129S6SvEvTacC57BL6CBACol8a2tm11AsjCol8a2tm11AsjCol8a2tm11Asj
• abnormal Descemet membrane_Col8a2<tm1.1Asj>/Col8a2<tm1.1Asj>
  http://metadb.riken.jp/0004284I129S6SvEvTacC57BL6CBACol8a2tm11AsjCol8a2tm11AsjCol8a2tm11Asj

class

http://purl.org/net/cito/citesAsAuthority

• Col8a2<tm1.1Asj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305275