Maria Pia. Postiglione, et.al., Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex., Neuron, 2011, 72

http://rdf.ncbi.nlm.nih.gov/pubmed/22017987

Maria Pia. Postiglione, et.al., Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex., Neuron, 2011, 72

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304351
• Insc<tm1Jakn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304348
• Gt(ROSA)26Sor<tm1.1(CAG-Insc/GFP)Jakn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304352

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304351
• Insc<tm1Jakn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304348
• Gt(ROSA)26Sor<tm1.1(CAG-Insc/GFP)Jakn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304352

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron morphology_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0002882IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal cortical plate morphology_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0008439IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal neuronal precursor proliferation_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0004948IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• abnormal neuronal precursor proliferation_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0004948IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal cortical intermediate zone morphology_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0008457IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal stratification in cerebral cortex_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000790IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• decreased neuron number_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0008948IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• abnormal cerebral cortex morphology_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000788IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• abnormal brain development_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000913IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• abnormal radial glial cell morphology_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0003648IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal cerebral cortex morphology_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000788IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• decreased brain size_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000774IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• thickened cerebral cortex_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000789IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal cortical intermediate zone morphology_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0008457IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• enlarged lateral ventricles_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0008535IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• abnormal brain development_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000913IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal lateral ganglionic eminence morphology_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0004277IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• thin cortical plate_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0008441IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• seizures_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0002064IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• increased neuronal precursor cell number_Gt(ROSA)26Sor<tm1.1(CAG-Insc/GFP)Jakn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004980IC57BL6GtROSA26Sortm11CAGInscGFPJaknGtROSA26SorGtROSA26Sortm11CAGInscGFPJaknGtROSA26Sor
• increased neuron number_Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>/Gt(ROSA)26Sor<tm1(CAG-Bgeo,-Insc/GFP)Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0008947IC57BL6GtROSA26Sortm1CAGBgeoInscGFPJaknGtROSA26Sortm1CAGBgeoInscGFPJaknTgNescre1Wmz0TgNescre1WmzGtROSA26Sortm1CAGBgeoInscGFPJakn
• abnormal neuron morphology_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0002882IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• thin cerebral cortex_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0006254IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn
• abnormal stratification in cerebral cortex_Insc<tm1Jakn>/Insc<tm1Jakn>,Tg(Nes-cre)1Wmz/0
  http://metadb.riken.jp/0000790IC57BL6Insctm1JaknInsctm1JaknTgNescre1Wmz0TgNescre1WmzInsctm1Jakn