Min. Wan, et.al., Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity., Molecular and cellular biology, 2012, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/22037765

Min. Wan, et.al., Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity., Molecular and cellular biology, 2012, 32

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Akt1<tm2.1Mbb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317890
• Akt1<tm2Mbb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317852

class

http://purl.org/net/cito/citesAsAuthority

• Akt1<tm2.1Mbb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317890
• Akt1<tm2Mbb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317852

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased respiratory quotient_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0010379I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• hyperactivity_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0001399I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased insulin sensitivity_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0002891I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased adiponectin level_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0004892I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased circulating thyroxine level_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0005478I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased oxygen consumption_Akt1<tm1Mbb>/Akt1<tm1Mbb>
  http://metadb.riken.jp/0005289B6129P2Akt1tm1MbbAkt1tm1MbbAkt1tm1MbbAkt1tm1Mbb
• decreased susceptibility to diet-induced obesity_Akt1<tm1Mbb>/Akt1<tm1Mbb>
  http://metadb.riken.jp/0005659B6129P2Akt1tm1MbbAkt1tm1MbbAkt1tm1MbbAkt1tm1Mbb
• decreased circulating leptin level_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0005668I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased total body fat amount_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0010025I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased oxygen consumption_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0005289I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased percent body fat/body weight_Akt1<tm1Mbb>/Akt1<tm1Mbb>
  http://metadb.riken.jp/0005459B6129P2Akt1tm1MbbAkt1tm1MbbAkt1tm1MbbAkt1tm1Mbb
• decreased susceptibility to hepatic steatosis_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0002310I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased carbon dioxide production_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0008963I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased basal metabolism_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0008965I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• improved glucose tolerance_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0005292I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased basal metabolism_Akt1<tm1Mbb>/Akt1<tm1Mbb>
  http://metadb.riken.jp/0008965B6129P2Akt1tm1MbbAkt1tm1MbbAkt1tm1MbbAkt1tm1Mbb
• abnormal gluconeogenesis_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0003383I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased body weight_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased lean body mass_Akt1<tm1Mbb>/Akt1<tm1Mbb>
  http://metadb.riken.jp/0003961B6129P2Akt1tm1MbbAkt1tm1MbbAkt1tm1MbbAkt1tm1Mbb
• decreased susceptibility to diet-induced obesity_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0005659I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• increased carbon dioxide production_Akt1<tm1Mbb>/Akt1<tm1Mbb>
  http://metadb.riken.jp/0008963B6129P2Akt1tm1MbbAkt1tm1MbbAkt1tm1MbbAkt1tm1Mbb
• increased fatty acid oxidation_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0014171I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased body size_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0001265I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased percent body fat/body weight_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0005459I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased body weight_Akt1<tm1Mbb>/Akt1<tm1Mbb>
  http://metadb.riken.jp/0001262B6129P2Akt1tm1MbbAkt1tm1MbbAkt1tm1MbbAkt1tm1Mbb
• decreased liver triglyceride level_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0009356I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• decreased lean body mass_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0003961I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb
• abnormal glucose homeostasis_Akt1<tm2.1Mbb>/Akt1<tm2.1Mbb>
  http://metadb.riken.jp/0002078I129S4SvJaeC57BL6JFVBNAkt1tm21MbbAkt1tm21MbbAkt1tm21Mbb