Atsushi. Hoshino, et.al., p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia., Journal of molecular and cellular cardiology, 2012, 52

http://rdf.ncbi.nlm.nih.gov/pubmed/22044588

Atsushi. Hoshino, et.al., p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia., Journal of molecular and cellular cardiology, 2012, 52

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tigar<tm1.2Smat>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319187
• Tigar<tm1.1Smat>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319186

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal autophagy_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0008260I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj
• altered response to myocardial infarction_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0000343I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• abnormal mitochondrial chromosome morphology_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0011638I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj
• abnormal heart morphology_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0000266I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj
• abnormal autophagy_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0008260I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• increased cardiac muscle contractility_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0005599I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj
• decreased cardiomyocyte apoptosis_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0003223I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• abnormal mitochondrial physiology_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0006036I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• increased cardiac muscle contractility_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0005599I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• oxidative stress_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0003674I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• abnormal heart morphology_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0000266I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• decreased cardiomyocyte apoptosis_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0003223I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj
• oxidative stress_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0003674I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj
• abnormal mitochondrial chromosome morphology_Tigar<tm1.2Smat>/Tigar<tm1.2Smat>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0011638I129S1Sv129X1SvJC57BL6JJclC57BL6NCrjTigartm12SmatTigartm12SmatTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTigartm12Smat
• abnormal mitochondrial physiology_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0006036I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj
• altered response to myocardial infarction_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
  http://metadb.riken.jp/0000343I129S2SvPasC57BL6C57BL6NCrjTrp53tm1TyjTrp53tm1TyjTgCAGEGFPMap1lc3b53Nmz0TgCAGEGFPMap1lc3b53NmzTrp53tm1Tyj

class

http://purl.org/net/cito/citesAsAuthority

• Tigar<tm1.2Smat>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319187
• Tigar<tm1.1Smat>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319186

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

BRC マウスの系統

http://metadb.riken.jp/db/rikenbrc_mouse/publications

• GFP-LC3#53
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC00806

BRC マウスの系統

http://purl.org/dc/terms/references

• GFP-LC3#53
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC00806

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]