Jianliang. Song, et.al., Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger., American journal of physiology. Heart and circulatory physiology, 2012, 302

http://rdf.ncbi.nlm.nih.gov/pubmed/22081699

Jianliang. Song, et.al., Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger., American journal of physiology. Heart and circulatory physiology, 2012, 302

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6*/tetO-FXYD1*S68E)39Jych
  http://metadb.riken.jp/db/mgi_rdf/MGI:5752796

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6*/tetO-FXYD1*S68E)39Jych
  http://metadb.riken.jp/db/mgi_rdf/MGI:5752796

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ventricular tachycardia_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0008950IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• increased heart left ventricle size_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0010579IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• cardiac hypertrophy_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0001625IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• ventricular fibrillation_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0006110IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• premature death_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0002083IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• increased ventricle muscle contractility_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0005600IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• abnormal cardiac muscle contractility_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0002972IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• increased cardiac stroke volume_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0011951IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• abnormal action potential_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0005402IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• abnormal myocardial fiber physiology_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0004215IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• decreased heart rate_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0005333IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• abnormal sinus arrhythmia_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0004122IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• decreased body size_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0001265IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych
• decreased cardiac output_Tg(Myh6*/tetO-FXYD1*S68E)39Jych/0,Tg(Myh6-tTA)55Rbns/0
  http://metadb.riken.jp/0003393IFVBNTgMyh6tetOFXYD1S68E39Jych0TgMyh6tTA55Rbns0TgMyh6tTA55RbnsTgMyh6tetOFXYD1S68E39Jych