Bettina. Platt, et.al., Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1., PloS one, 2011, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/22096518

Bettina. Platt, et.al., Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1., PloS one, 2011, 6

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428335

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal spatial working memory_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0008428I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• fragmentation of sleep/wake states_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0009436I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• decreased paired-pulse facilitation_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0002920I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• abnormal motor coordination/ balance_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0001516I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• abnormal long term potentiation_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0002207I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• abnormal spatial reference memory_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0008414I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• abnormal learning/memory/conditioning_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0002063I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• abnormal glucose homeostasis_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0002078I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• abnormal brain wave pattern_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0004994I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• abnormal short term object recognition memory_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0002800I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno
• hyperactivity_Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>/Hprt<+>,Tg(PSEN1)5Dbo/0
  http://metadb.riken.jp/0001399I129P2OlaHsdHprttm1Camk2aAPPSweLonMAPTP301LR406WGenoHprtTgPSEN15Dbo0TgPSEN15DboHprtHprttm1Camk2aAPPSweLonMAPTP301LR406WGeno

class

http://purl.org/net/cito/citesAsAuthority

• Hprt<tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428335