Marie. Lia, et.al., Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines., Blood, 2012, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/22174151

Marie. Lia, et.al., Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines., Blood, 2012, 119

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Del(14Trim13-Rnaseh2b)6Rdf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304666
• Is(14)5Rdf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304347

class

http://purl.org/net/cito/citesAsAuthority

• Del(14Trim13-Rnaseh2b)6Rdf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304666
• Is(14)5Rdf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304347

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased chronic lymphocytic leukemia incidence_Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0010337I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs145RdfDel14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfIs141RdfIs145RdfCd19tm1creCgn
• increased small lymphocytic lymphoma incidence_Del(14Trim13-Rnaseh2b)6Rdf/+,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0009319I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Del14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfCd19tm1creCgn
• abnormal lymphopoiesis_Del(14Trim13-Rnaseh2b)6Rdf/+,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002401I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Del14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfCd19tm1creCgn
• embryonic lethality, complete penetrance_Del(14Trim13-Rnaseh2b)6Rdf/Del(14Trim13-Rnaseh2b)6Rdf
  http://metadb.riken.jp/0011092I129S1Sv129S4SvJaeSorC57BL6Del14Trim13Rnaseh2b6RdfDel14Trim13Rnaseh2b6RdfDel14Trim13Rnaseh2b6Rdf
• increased lymphoma incidence_Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0012431I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs145RdfDel14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfIs141RdfIs145RdfCd19tm1creCgn
• abnormal lymphopoiesis_Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002401I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs145RdfDel14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfIs141RdfIs145RdfCd19tm1creCgn
• increased chronic lymphocytic leukemia incidence_Is(14)1Rdf/Is(14)1Rdf,Is(14)5Rdf/Is(14)5Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0010337I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs141RdfIs145RdfIs145RdfCd19tm1creCgnCd19Is141RdfIs145RdfCd19Cd19tm1creCgn
• abnormal lymphopoiesis_Is(14)1Rdf/Is(14)1Rdf,Is(14)5Rdf/Is(14)5Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002401I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs141RdfIs145RdfIs145RdfCd19tm1creCgnCd19Is141RdfIs145RdfCd19Cd19tm1creCgn
• increased small lymphocytic lymphoma incidence_Is(14)1Rdf/Is(14)1Rdf,Is(14)5Rdf/Is(14)5Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0009319I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs141RdfIs145RdfIs145RdfCd19tm1creCgnCd19Is141RdfIs145RdfCd19Cd19tm1creCgn
• increased lymphoma incidence_Del(14Trim13-Rnaseh2b)6Rdf/+,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0012431I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Del14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfCd19tm1creCgn
• premature death_Del(14Trim13-Rnaseh2b)6Rdf/+,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Del14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfCd19tm1creCgn
• increased B cell number_Del(14Trim13-Rnaseh2b)6Rdf/+,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0005014I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Del14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfCd19tm1creCgn
• increased small lymphocytic lymphoma incidence_Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0009319I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs145RdfDel14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfIs141RdfIs145RdfCd19tm1creCgn
• increased chronic lymphocytic leukemia incidence_Del(14Trim13-Rnaseh2b)6Rdf/+,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0010337I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Del14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfCd19tm1creCgn
• premature death_Is(14)1Rdf/Is(14)1Rdf,Is(14)5Rdf/Is(14)5Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs141RdfIs145RdfIs145RdfCd19tm1creCgnCd19Is141RdfIs145RdfCd19Cd19tm1creCgn
• premature death_Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs145RdfDel14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfIs141RdfIs145RdfCd19tm1creCgn
• increased lymphoma incidence_Is(14)1Rdf/Is(14)1Rdf,Is(14)5Rdf/Is(14)5Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0012431I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs141RdfIs145RdfIs145RdfCd19tm1creCgnCd19Is141RdfIs145RdfCd19Cd19tm1creCgn
• increased B cell number_Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0005014I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs145RdfDel14Trim13Rnaseh2b6RdfCd19tm1creCgnCd19Cd19Del14Trim13Rnaseh2b6RdfIs141RdfIs145RdfCd19tm1creCgn
• increased B cell number_Is(14)1Rdf/Is(14)1Rdf,Is(14)5Rdf/Is(14)5Rdf,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0005014I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Is141RdfIs141RdfIs145RdfIs145RdfCd19tm1creCgnCd19Is141RdfIs145RdfCd19Cd19tm1creCgn