Dick. Jaarsma, et.al., Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology., PLoS genetics, 2011, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/22174697

Dick. Jaarsma, et.al., Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology., PLoS genetics, 2011, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Xpa<tm1Gvh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5312129

class

http://purl.org/net/cito/citesAsAuthority

• Xpa<tm1Gvh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5312129

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hippocampus atrophy_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0030003I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• increased thigmotaxis_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0002797I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• astrocytosis_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0003354I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• astrocytosis_Ercc8<tm1Jhjh>/Ercc8<tm1Jhjh>
  http://metadb.riken.jp/0003354I129P2OlaHsdC57BL6JErcc8tm1JhjhErcc8tm1JhjhErcc8tm1Jhjh
• decreased body weight_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• abnormal gait_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001406I129P2OlaHsdC57BL6C57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCAGcre13Miya0Xpatm1GvhErcc6tm1GvhXpatm1HvsTgCAGcre13Miya
• seizures_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0002064I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• decreased body size_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• astrocytosis_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>
  http://metadb.riken.jp/0003354I129P2OlaHsdC57BL6JErcc6tm1GvhErcc6tm1GvhErcc6tm1Gvh
• astrocytosis_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0003354I129P2OlaHsd129S1Sv129X1SvJC57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgPcp2cre2Mpin0Ercc6tm1GvhXpatm1GvhTgPcp2cre2MpinXpatm1Hvs
• increased cellular sensitivity to ultraviolet irradiation_Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0008410I129P2OlaHsdC57BL6C57BL6JXpatm1GvhXpatm1HvsTgCAGcre13Miya0Xpatm1GvhTgCAGcre13MiyaXpatm1Hvs
• postnatal growth retardation_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6C57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCAGcre13Miya0Xpatm1GvhErcc6tm1GvhXpatm1HvsTgCAGcre13Miya
• microgliosis_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0008918I129P2OlaHsd129S1Sv129X1SvJC57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgPcp2cre2Mpin0Ercc6tm1GvhXpatm1GvhTgPcp2cre2MpinXpatm1Hvs
• decreased cellular sensitivity to ultraviolet irradiation_Xpa<tm1Gvh>/Xpa<tm1Hvs>
  http://metadb.riken.jp/0008411I129P2OlaHsdC57BL6JXpatm1GvhXpatm1HvsXpatm1GvhXpatm1Hvs
• Purkinje cell degeneration_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0000876I129P2OlaHsd129S1Sv129X1SvJC57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgPcp2cre2Mpin0Ercc6tm1GvhXpatm1GvhTgPcp2cre2MpinXpatm1Hvs
• abnormal cerebral cortex morphology_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0000788I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• postnatal lethality, complete penetrance_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0011085I129P2OlaHsdC57BL6C57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCAGcre13Miya0Xpatm1GvhErcc6tm1GvhXpatm1HvsTgCAGcre13Miya
• microgliosis_Ercc8<tm1Jhjh>/Ercc8<tm1Jhjh>
  http://metadb.riken.jp/0008918I129P2OlaHsdC57BL6JErcc8tm1JhjhErcc8tm1JhjhErcc8tm1Jhjh
• microgliosis_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0008918I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• microgliosis_Ercc2<tm3Jhjh>/Ercc2<tm3Jhjh>
  http://metadb.riken.jp/0008918I129C57BL6JErcc2tm3JhjhErcc2tm3JhjhErcc2tm3Jhjh
• abnormal telencephalon morphology_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0000787I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• microgliosis_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>
  http://metadb.riken.jp/0008918I129P2OlaHsdC57BL6JErcc6tm1GvhErcc6tm1GvhErcc6tm1Gvh
• premature death_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• cachexia_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0005150I129P2OlaHsdC57BL6C57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCAGcre13Miya0Xpatm1GvhErcc6tm1GvhXpatm1HvsTgCAGcre13Miya
• abnormal neocortex morphology_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0008547I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• impaired coordination_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0001405I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• neuron degeneration_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0003224I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• abnormal dorsal striatum morphology_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0004102I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• dilated lateral ventricles_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0000825I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh
• astrocytosis_Ercc2<tm3Jhjh>/Ercc2<tm3Jhjh>
  http://metadb.riken.jp/0003354I129C57BL6JErcc2tm3JhjhErcc2tm3JhjhErcc2tm3Jhjh
• axon degeneration_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0005405I129P2OlaHsd129S1Sv129X1SvJC57BL6JErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgPcp2cre2Mpin0Ercc6tm1GvhXpatm1GvhTgPcp2cre2MpinXpatm1Hvs
• thin cerebral cortex_Ercc6<tm1Gvh>/Ercc6<tm1Gvh>,Xpa<tm1Gvh>/Xpa<tm1Hvs>,Tg(Camk2a-cre)1Szi/0
  http://metadb.riken.jp/0006254I129P2OlaHsdC57BL6JCBAErcc6tm1GvhErcc6tm1GvhXpatm1GvhXpatm1HvsTgCamk2acre1Szi0Xpatm1HvsXpatm1GvhTgCamk2acre1SziErcc6tm1Gvh