Anthie. Yiakouvaki, et.al., Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis., The Journal of clinical investigation, 2012, 122

http://rdf.ncbi.nlm.nih.gov/pubmed/22201685

Anthie. Yiakouvaki, et.al., Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis., The Journal of clinical investigation, 2012, 122

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Elavl1<tm1.1Dkon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437584

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased incidence of tumors by chemical induction_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0004499B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased sensitivity to xenobiotic induced morbidity/mortality_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0009766B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased circulating interleukin-1 beta level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008641B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• decreased tumor growth/size_Tg(LYS2-rtTA2S*M2,tetO-ELAVL1)632Dkon/0
  http://metadb.riken.jp/0003447B6CgTgLYS2rtTA2SM2tetOELAVL1632DkonTgLYS2rtTA2SM2tetOELAVL1632Dkon0TgLYS2rtTA2SM2tetOELAVL1632Dkon
• increased susceptibility to induced colitis_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008537B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased susceptibility to endotoxin shock_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008735I129P2OlaHsdC57BL6JElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoElavl1tm11Dkon
• increased susceptibility to endotoxin shock_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008735B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased tumor growth/size_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0003721B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased circulating tumor necrosis factor level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008553B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased circulating interleukin-1 beta level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008641I129P2OlaHsdC57BL6JElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoElavl1tm11Dkon
• increased colonic adenoma incidence_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0002044B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased circulating interleukin-6 level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008596I129P2OlaHsdC57BL6JElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoElavl1tm11Dkon
• increased circulating interleukin-12 level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008617I129P2OlaHsdC57BL6JElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoElavl1tm11Dkon
• decreased susceptibility to induced colitis_Tg(LYS2-rtTA2S*M2,tetO-ELAVL1)632Dkon/0
  http://metadb.riken.jp/0008539B6CgTgLYS2rtTA2SM2tetOELAVL1632DkonTgLYS2rtTA2SM2tetOELAVL1632Dkon0TgLYS2rtTA2SM2tetOELAVL1632Dkon
• decreased incidence of tumors by chemical induction_Tg(LYS2-rtTA2S*M2,tetO-ELAVL1)632Dkon/0
  http://metadb.riken.jp/0004502B6CgTgLYS2rtTA2SM2tetOELAVL1632DkonTgLYS2rtTA2SM2tetOELAVL1632Dkon0TgLYS2rtTA2SM2tetOELAVL1632Dkon
• increased colon adenocarcinoma incidence_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0009314B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased circulating tumor necrosis factor level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008553I129P2OlaHsdC57BL6JElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoElavl1tm11Dkon
• increased circulating interleukin-12 level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008617B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased macrophage cell number_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0005425B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased sensitivity to xenobiotic induced morbidity/mortality_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0009766I129P2OlaHsdC57BL6JElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoElavl1tm11Dkon
• abnormal macrophage chemotaxis_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0010760B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased monocyte cell number_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0000220B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo
• increased circulating interleukin-6 level_Elavl1<tm1.1Dkon>/Elavl1<tm1.1Dkon>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008596B6129P2Elavl1tm11DkonLyz2tm1creIfoElavl1tm11DkonElavl1tm11DkonLyz2tm1creIfoLyz2Elavl1tm11DkonLyz2Lyz2tm1creIfo

class

http://purl.org/net/cito/citesAsAuthority

• Elavl1<tm1.1Dkon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437584