Cristina. Aguirre-Portolés, et.al., Tpx2 controls spindle integrity, genome stability, and tumor development., Cancer research, 2012, 72

http://rdf.ncbi.nlm.nih.gov/pubmed/22266221

Cristina. Aguirre-Portolés, et.al., Tpx2 controls spindle integrity, genome stability, and tumor development., Cancer research, 2012, 72

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tpx2<Gt(D028B03)1.1Wrst>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5426862
• Tpx2<Gt(D028B03)1.2Wrst>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5426857

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• polyploidy_Tpx2<Gt(D028B03)1.1Wrst>/Tpx2<Gt(D028B03)1.1Wrst>
  http://metadb.riken.jp/0004025I129S2SvPasC57BL6JTpx2GtD028B0311WrstTpx2GtD028B0311WrstTpx2GtD028B0311Wrst
• aneuploidy_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0004024I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• increased lung adenoma incidence_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0002048I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• abnormal mitosis_Tpx2<Gt(D028B03)1.1Wrst>/Tpx2<Gt(D028B03)1.1Wrst>
  http://metadb.riken.jp/0004046I129S2SvPasC57BL6JTpx2GtD028B0311WrstTpx2GtD028B0311WrstTpx2GtD028B0311Wrst
• abnormal mitotic spindle morphology_Tpx2<Gt(D028B03)Wrst>/Tpx2<Gt(D028B03)Wrst>
  http://metadb.riken.jp/0009760I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2GtD028B03WrstTpx2GtD028B03Wrst
• increased metastatic potential_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0001272I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• decreased cell proliferation_Tpx2<Gt(D028B03)1.1Wrst>/Tpx2<Gt(D028B03)1.1Wrst>
  http://metadb.riken.jp/0000352I129S2SvPasC57BL6JTpx2GtD028B0311WrstTpx2GtD028B0311WrstTpx2GtD028B0311Wrst
• increased stomach tumor incidence_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0010301I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• abnormal embryo development_Tpx2<Gt(D028B03)Wrst>/Tpx2<Gt(D028B03)Wrst>
  http://metadb.riken.jp/0001672I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2GtD028B03WrstTpx2GtD028B03Wrst
• abnormal embryo development_Tpx2<Gt(D028B03)1.2Wrst>/Tpx2<Gt(D028B03)1.2Wrst>
  http://metadb.riken.jp/0001672I129S2SvPasC57BL6JTpx2GtD028B0312WrstTpx2GtD028B0312WrstTpx2GtD028B0312Wrst
• increased lung adenocarcinoma incidence_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0002027I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• abnormal mitotic spindle assembly checkpoint_Tpx2<Gt(D028B03)1.1Wrst>/Tpx2<Gt(D028B03)1.1Wrst>
  http://metadb.riken.jp/0009762I129S2SvPasC57BL6JTpx2GtD028B0311WrstTpx2GtD028B0311WrstTpx2GtD028B0311Wrst
• increased hepatocellular carcinoma incidence_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0003331I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• abnormal splenocyte morphology_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0009332I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• polyploidy_Tpx2<Gt(D028B03)Wrst>/Tpx2<Gt(D028B03)Wrst>
  http://metadb.riken.jp/0004025I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2GtD028B03WrstTpx2GtD028B03Wrst
• increased intestinal adenoma incidence_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0002404I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• pituitary intermediate lobe hyperplasia_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0008371I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• granulomatous inflammation_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0002500I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• increased lymphoma incidence_Tpx2<Gt(D028B03)Wrst>/Tpx2<+>
  http://metadb.riken.jp/0012431I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2Tpx2Tpx2GtD028B03Wrst
• abnormal cell nucleus morphology_Tpx2<Gt(D028B03)1.1Wrst>/Tpx2<Gt(D028B03)1.1Wrst>
  http://metadb.riken.jp/0003111I129S2SvPasC57BL6JTpx2GtD028B0311WrstTpx2GtD028B0311WrstTpx2GtD028B0311Wrst
• embryonic growth arrest_Tpx2<Gt(D028B03)Wrst>/Tpx2<Gt(D028B03)Wrst>
  http://metadb.riken.jp/0001730I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2GtD028B03WrstTpx2GtD028B03Wrst
• embryonic lethality, complete penetrance_Tpx2<Gt(D028B03)Wrst>/Tpx2<Gt(D028B03)Wrst>
  http://metadb.riken.jp/0011092I129S2SvPasC57BL6JTpx2GtD028B03WrstTpx2GtD028B03WrstTpx2GtD028B03Wrst

class

http://purl.org/net/cito/citesAsAuthority

• Tpx2<Gt(D028B03)1.1Wrst>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5426862
• Tpx2<Gt(D028B03)1.2Wrst>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5426857