Dong. Chen, et.al., Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis., Current biology : CB, 2012, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/22342750

Dong. Chen, et.al., Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis., Current biology : CB, 2012, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pum1<tm1.1Hfl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5316376
• Pum1<tm1.2Hfl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5316377

class

http://purl.org/net/cito/citesAsAuthority

• Pum1<tm1.1Hfl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5316376
• Pum1<tm1.2Hfl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5316377

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small seminiferous tubules_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001153I129S2SvPasC57BL6FVBPum1tm12HflPum1tm12HflTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjPum1tm12Hfl
• abnormal male germ cell apoptosis_Pum1<tm1.2Hfl>/Pum1<+>
  http://metadb.riken.jp/0008280I129C57BL6FVBPum1tm12HflPum1Pum1tm12HflPum1
• decreased testis weight_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0004852I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl
• decreased body weight_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0001262I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl
• abnormal male germ cell apoptosis_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0008280I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl
• testis hypoplasia_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0001940I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl
• oligozoospermia_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0002687I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl
• small seminiferous tubules_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0001153I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl
• oligozoospermia_Pum1<tm1.2Hfl>/Pum1<+>
  http://metadb.riken.jp/0002687I129C57BL6FVBPum1tm12HflPum1Pum1tm12HflPum1
• reduced male fertility_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0001922I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl
• abnormal male germ cell apoptosis_Pum1<tm1.1Hfl>/Pum1<tm1.2Hfl>,Tg(Ddx4-cre)1Dcas/0
  http://metadb.riken.jp/0008280I129C57BL6FVBPum1tm11HflPum1tm12HflTgDdx4cre1Dcas0Pum1tm12HflPum1tm11HflTgDdx4cre1Dcas
• abnormal spermatogenesis_Pum1<tm1.2Hfl>/Pum1<tm1.2Hfl>
  http://metadb.riken.jp/0001156I129C57BL6FVBPum1tm12HflPum1tm12HflPum1tm12Hfl