Silayuv E. Bongfen, et.al., An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/22363534

Silayuv E. Bongfen, et.al., An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria., PloS one, 2012, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Jak3<M1Pgrs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468008

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small thymus_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0000706IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• decreased NK cell number_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0008045IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• absent B cells_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0008071IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• decreased susceptibility to parasitic infection induced morbidity/mortality_Jak3<M1Pgrs>/Jak3<+>
  http://metadb.riken.jp/0010751IC57BL6JC57BL10JJak3M1PgrsJak3Jak3M1PgrsJak3
• increased susceptibility to bacterial infection_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0002412IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• decreased susceptibility to parasitic infection induced morbidity/mortality_Jak3<M1Pgrs>/Jak3<tm1Ljb>
  http://metadb.riken.jp/0010751I129S4SvJaeC57BL6JC57BL10JJak3M1PgrsJak3tm1LjbJak3M1PgrsJak3tm1Ljb
• decreased B cell number_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0005017IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• enlarged spleen_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0000691IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• decreased hematopoietic stem cell number_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0004810IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• decreased interferon-gamma secretion_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0008567IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• increased CD4-positive, alpha beta T cell number_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0008074IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• decreased susceptibility to parasitic infection induced morbidity/mortality_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0010751IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• increased CD8-positive, alpha-beta T cell number_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0008078IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs
• increased susceptibility to bacterial infection induced morbidity/mortality_Jak3<M1Pgrs>/Jak3<M1Pgrs>
  http://metadb.riken.jp/0009788IC57BL6JC57BL10JJak3M1PgrsJak3M1PgrsJak3M1Pgrs

class

http://purl.org/net/cito/citesAsAuthority

• Jak3<M1Pgrs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468008