Emilie. Mugniery, et.al., An activating Fgfr3 mutation affects trabecular bone formation via a paracrine mechanism during growth., Human molecular genetics, 2012, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/22367969

Emilie. Mugniery, et.al., An activating Fgfr3 mutation affects trabecular bone formation via a paracrine mechanism during growth., Human molecular genetics, 2012, 21

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased length of long bones_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0004686I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal bone structure_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0003795I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• decreased width of hypertrophic chondrocyte zone_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0003409I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal skeleton development_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0002113I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal trabecular bone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0000130I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal long bone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0003723I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• short ribs_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0004672I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• decreased body size_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0001265I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal long bone epiphyseal ossification zone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0006399I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal long bone epiphysis morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0000131I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal long bone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0003723I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal bone mineralization_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0002896I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• domed cranium_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0000440I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal long bone epiphysis morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0000131I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• decreased body size_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0001265I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• short ribs_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0004672I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal axial skeleton morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0002114I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• decreased length of long bones_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0004686I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• domed cranium_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0000440I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal skeleton development_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0002113I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal trabecular bone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0000130I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• increased osteoclast cell number_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0004984I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal axial skeleton morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0002114I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal bone mineralization_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0002896I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal long bone epiphyseal plate proliferative zone_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0003662I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal long bone epiphyseal plate morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0003055I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• delayed bone ossification_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0000060I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal thoracic cage morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0004624I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• increased osteoclast cell number_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0004984I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal craniofacial bone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0002116I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal craniofacial bone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0002116I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal bone structure_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(CMV-cre)1Ipc/?
  http://metadb.riken.jp/0003795I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCMVcre1IpcFgfr3TgCMVcre1IpcFgfr3tm2Llm
• abnormal thoracic cage morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0004624I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm
• abnormal long bone epiphyseal ossification zone morphology_Fgfr3<tm2Llm>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/?
  http://metadb.riken.jp/0006399I129S2SvPasC57BL6SJLFgfr3tm2LlmFgfr3TgCol2a1cre1BhrTgCol2a1cre1BhrFgfr3Fgfr3tm2Llm