Elisa S. Na, et.al., A mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmission., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/22378884

Elisa S. Na, et.al., A mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmission., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enhanced paired-pulse facilitation_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0002919B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• decreased body weight_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0001262B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• increased anxiety-related response_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0001363B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• abnormal associative learning_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0002062B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• abnormal miniature excitatory postsynaptic currents_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0004753B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• abnormal object recognition memory_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0001458B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• reduced long term potentiation_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0001473B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• impaired coordination_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0001405B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• abnormal contextual conditioning behavior_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0001469B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae
• abnormal cued conditioning behavior_Mapt<tm1(Mecp2)Jae>/Mapt<tm1(Mecp2)Jae>
  http://metadb.riken.jp/0001454B6CgMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2JaeMapttm1Mecp2Jae