Johan H. van Es, et.al., A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal., Molecular and cellular biology, 2012, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/22393260

Johan H. van Es, et.al., A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal., Molecular and cellular biology, 2012, 32

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tcf7l2<tm2.1Cle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430317

class

http://purl.org/net/cito/citesAsAuthority

• Tcf7l2<tm2.1Cle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430317

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ectopic Paneth cells_Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0014077I129P2OlaHsdC57BL6DBA2Tcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrTcf7l2tm21Cle
• decreased Paneth cell number_Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0013486I129P2OlaHsdC57BL6DBA2Tcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrTcf7l2tm21Cle
• increased enterocyte apoptosis_Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008885I129P2OlaHsdC57BL6DBA2Tcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrTcf7l2tm21Cle
• abnormal enterocyte proliferation_Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008883I129P2OlaHsdC57BL6DBA2Tcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrTcf7l2tm21Cle
• abnormal digestive system morphology_Tcf7<tm1Cle>/Tcf7<tm1Cle>,Tcf7l1<tm1Efu>/Tcf7l1<tm1Efu>,Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0000462I129P2OlaHsdC57BL6DBA2Tcf7tm1CleTcf7tm1CleTcf7l1tm1EfuTcf7l1tm1EfuTcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0Tcf7l2tm21CleTcf7tm1CleTcf7l1tm1EfuTgVilcreERT223Syr
• abnormal digestive system physiology_Tcf7<tm1Cle>/Tcf7<tm1Cle>,Tcf7l1<tm1Efu>/Tcf7l1<tm1Efu>,Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0001663I129P2OlaHsdC57BL6DBA2Tcf7tm1CleTcf7tm1CleTcf7l1tm1EfuTcf7l1tm1EfuTcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0Tcf7l2tm21CleTcf7tm1CleTcf7l1tm1EfuTgVilcreERT223Syr
• absent Paneth cells_Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0014076I129P2OlaHsdC57BL6DBA2Tcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrTcf7l2tm21Cle
• abnormal small intestine goblet cell morphology_Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0013792I129P2OlaHsdC57BL6DBA2Tcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrTcf7l2tm21Cle
• abnormal intestine development_Tcf7l2<tm2.1Cle>/Tcf7l2<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0010158I129P2OlaHsdC57BL6DBA2Tcf7l2tm21CleTcf7l2tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrTcf7l2tm21Cle