Anne. Gegonne, et.al., The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells., Molecular and cellular biology, 2012, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/22411629

http://rdf.ncbi.nlm.nih.gov/pubmed/22411629

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Taf7<tm1.2Dss>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430373
• Taf7<tm1.1Dss>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430372

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD8-positive, alpha-beta T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008079IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss
• decreased thymocyte number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0000715IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• decreased CD4-positive, alpha beta T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008075IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• decreased thymocyte number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0000715IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss
• decreased single-positive T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008083IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss
• decreased T cell proliferation_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0005095IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss
• abnormal T cell differentiation_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0002145IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss
• abnormal thymus physiology_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0003763IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• decreased T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0005018IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss
• increased double-negative T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005090IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• decreased CD8-positive, alpha-beta T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008079IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• small thymus_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0000706IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• abnormal embryo development_Taf7<tm1.1Dss>/Taf7<tm1.1Dss>
  http://metadb.riken.jp/0001672IC57BL6Taf7tm11DssTaf7tm11DssTaf7tm11Dss
• decreased CD4-positive, alpha beta T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008075IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss
• decreased double-positive T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005092IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• abnormal T cell differentiation_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0002145IC57BL6Taf7tm11DssTaf7tm12DssTgLckcre1Cwi0Taf7tm12DssTgLckcre1CwiTaf7tm11Dss
• embryonic lethality, complete penetrance_Taf7<tm1.1Dss>/Taf7<tm1.1Dss>
  http://metadb.riken.jp/0011092IC57BL6Taf7tm11DssTaf7tm11DssTaf7tm11Dss
• decreased double-positive T cell number_Taf7<tm1.1Dss>/Taf7<tm1.2Dss>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0005092IC57BL6Taf7tm11DssTaf7tm12DssTgCd8acreAsin0Taf7tm11DssTgCd8acreAsinTaf7tm12Dss

class

http://purl.org/net/cito/citesAsAuthority

• Taf7<tm1.2Dss>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430373
• Taf7<tm1.1Dss>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430372