Janice Ching. Lai, et.al., The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis., Blood, 2012, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/22422825

Janice Ching. Lai, et.al., The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis., Blood, 2012, 119

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dhx36<tm1.1Pmt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427959
• Dhx36<tm1.2Pmt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427960

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal erythropoiesis_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000245I129P2Ola129S4SvJaeSorC57BL6CBADhx36tm12PmtDhx36tm12PmtTgMx1cre1Cgn0Dhx36tm12PmtTgMx1cre1Cgn
• enlarged spleen_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0000691I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• decreased granulocyte monocyte progenitor cell number_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0013697I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• pallor_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0003717I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• abnormal proerythroblast morphology_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0002416I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• intermingled spleen red and white pulp_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0008475I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• spherocytosis_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0002812I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• reticulocytosis_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0002640I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• abnormal erythrocyte physiology_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0003656I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• decreased erythroblast number_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0011179I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• enlarged liver_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0000599I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• abnormal erythropoiesis_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0000245I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• increased erythroblast number_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0011178I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• decreased hemoglobin content_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0002874I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• increased hematopoietic stem cell number_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0004809I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• hemolytic anemia_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0001585I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• pale kidney_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0004969I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• abnormal cell cycle_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0003077I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• abnormal leukopoiesis_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005460I129P2Ola129S4SvJaeSorC57BL6CBADhx36tm12PmtDhx36tm12PmtTgMx1cre1Cgn0Dhx36tm12PmtTgMx1cre1Cgn
• increased megakaryocyte-erythroid progenitor cell number_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0013704I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• embryonic lethality between implantation and somite formation, complete penetrance_Dhx36<tm1.1Pmt>/Dhx36<tm1.1Pmt>
  http://metadb.riken.jp/0011096I129P2OlaC57BL6Dhx36tm11PmtDhx36tm11PmtDhx36tm11Pmt
• anemia_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0001577I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• increased mean corpuscular volume_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0002590I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• thymus hypoplasia_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0001823I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• pale liver_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0000603I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio
• decreased erythrocyte cell number_Dhx36<tm1.2Pmt>/Dhx36<tm1.2Pmt>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0002875I129P2Ola129S4SvJaeSorC57BL6C57BL10CBACaDhx36tm12PmtDhx36tm12PmtTgVav1icreA2Kio0Dhx36tm12PmtTgVav1icreA2Kio

class

http://purl.org/net/cito/citesAsAuthority

• Dhx36<tm1.1Pmt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427959
• Dhx36<tm1.2Pmt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427960