Liren. Liu, et.al., Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis., Cell research, 2012, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/22453236

Liren. Liu, et.al., Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis., Cell research, 2012, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cul4b<tm1.1Pz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5502166

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent ectoplacental cone_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001717I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• abnormal ectoderm development_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001675I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• no abnormal phenotype detected_Cul4b<tm1.1Pz>/Y
  http://metadb.riken.jp/0002169I129C57BL6JCul4btm11PzYCul4btm11Pz
• increased embryonic tissue cell apoptosis_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0013504I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• decreased cell proliferation_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0000352I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• abnormal embryo development_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001672I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• abnormal vitelline vasculature morphology_Cul4b<tm1.1Pz>/Cul4b<+>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0003229I129C57BL6C57BL6JCul4btm11PzCul4bTgCAGcre13Miya0TgCAGcre13MiyaCul4bCul4btm11Pz
• no abnormal phenotype detected_Cul4b<tm1.1Pz>/Cul4b<tm1.1Pz>
  http://metadb.riken.jp/0002169I129C57BL6JCul4btm11PzCul4btm11PzCul4btm11Pz
• embryonic lethality during organogenesis, complete penetrance_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0011098I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• lethality throughout fetal growth and development, complete penetrance_Cul4b<tm1.1Pz>/Cul4b<+>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0011099I129C57BL6C57BL6JCul4btm11PzCul4bTgCAGcre13Miya0TgCAGcre13MiyaCul4bCul4btm11Pz
• no abnormal phenotype detected_Cul4b<tm1.1Pz>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002169I129C57BL6C57BL6JCBACul4btm11PzYTgSox2cre1Amc0TgSox2cre1AmcCul4btm11Pz
• failure of primitive streak formation_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001693I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• decreased embryo size_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001698I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz
• embryonic growth arrest_Cul4b<tm1.1Pz>/Y,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001730I129C57BL6C57BL6JCul4btm11PzYTgCAGcre13Miya0TgCAGcre13MiyaCul4btm11Pz

class

http://purl.org/net/cito/citesAsAuthority

• Cul4b<tm1.1Pz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5502166