Jian-Xin. Lin, et.al., Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function., Immunity, 2012, 36

http://rdf.ncbi.nlm.nih.gov/pubmed/22520852

Jian-Xin. Lin, et.al., Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function., Immunity, 2012, 36

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stat5a<tm1.1Wjl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437316
• Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437318

class

http://purl.org/net/cito/citesAsAuthority

• Stat5a<tm1.1Wjl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437316
• Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437318

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal regulatory T cell physiology_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0004946I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• decreased hemoglobin content_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0002874I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• increased T cell apoptosis_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0006413I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• decreased T cell proliferation_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0005095I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• decreased NK cell number_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0008045I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• no abnormal phenotype detected_Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0002169I129S6SvEvTacC57BL6JFVBNStat5btm21WjlStat5btm21WjlStat5btm21Wjl
• abnormal T cell subpopulation ratio_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0003944I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• no abnormal phenotype detected_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>
  http://metadb.riken.jp/0002169I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5atm11Wjl
• decreased hematocrit_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0000208I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• decreased CD8-positive, alpha-beta T cell number_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0008079I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• abnormal leukocyte morphology_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0008246I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl
• decreased erythrocyte cell number_Stat5a<tm1.1Wjl>/Stat5a<tm1.1Wjl>,Stat5b<tm2.1Wjl>/Stat5b<tm2.1Wjl>
  http://metadb.riken.jp/0002875I129S6SvEvTacC57BL6JFVBNStat5atm11WjlStat5atm11WjlStat5btm21WjlStat5btm21WjlStat5atm11WjlStat5btm21Wjl