Peili. Gu, et.al., CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion., The EMBO journal, 2012, 31

http://rdf.ncbi.nlm.nih.gov/pubmed/22531781

Peili. Gu, et.al., CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion., The EMBO journal, 2012, 31

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ctc1<tm1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427641
• Ctc1<tm1.1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427642

class

http://purl.org/net/cito/citesAsAuthority

• Ctc1<tm1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427641
• Ctc1<tm1.1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427642

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased cell proliferation_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0000352I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• sparse hair_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0000416I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• small spleen_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0000692I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• small thymus_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0000706I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• decreased body size_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0001265I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• impaired hematopoiesis_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0001606I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
他10件を見る
• premature death_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0002083I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• abnormal bone marrow cell morphology/development_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0002398I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• abnormal telomere length_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0003155I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• abnormal hematopoietic stem cell morphology_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0004808I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• decreased hematopoietic stem cell number_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0004810I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• early cellular replicative senescence_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0008008I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• abnormal DNA repair_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0008058I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• chromosomal instability_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0008866I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• decreased splenocyte proliferation_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0009335I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg
• decreased fibroblast proliferation_Ctc1<tm1.1Schg>/Ctc1<tm1.1Schg>
  http://metadb.riken.jp/0011704I129S7SvEvBrdC57BL6Ctc1tm11SchgCtc1tm11SchgCtc1tm11Schg