Zhenghong. Lin, et.al., USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development., Molecular cell, 2012, 46

http://rdf.ncbi.nlm.nih.gov/pubmed/22542455

Zhenghong. Lin, et.al., USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development., Molecular cell, 2012, 46

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Usp22<tm1Dfan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5441074

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased embryo size_Usp22<tm1Dfan>/Usp22<tm1Dfan>
  http://metadb.riken.jp/0001698C57BL6Usp22tm1DfanUsp22tm1DfanUsp22tm1DfanUsp22tm1Dfan
• embryonic lethality during organogenesis, complete penetrance_Usp22<tm1Dfan>/Usp22<tm1Dfan>
  http://metadb.riken.jp/0011098C57BL6Usp22tm1DfanUsp22tm1DfanUsp22tm1DfanUsp22tm1Dfan
• embryonic growth retardation_Usp22<tm1Dfan>/Usp22<tm1Dfan>
  http://metadb.riken.jp/0003984C57BL6Usp22tm1DfanUsp22tm1DfanUsp22tm1DfanUsp22tm1Dfan
• increased fibroblast apoptosis_Usp22<tm1Dfan>/Usp22<tm1Dfan>
  http://metadb.riken.jp/0013501C57BL6Usp22tm1DfanUsp22tm1DfanUsp22tm1DfanUsp22tm1Dfan

class

http://purl.org/net/cito/citesAsAuthority

• Usp22<tm1Dfan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5441074