Di. Wang, et.al., Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling., Nature immunology, 2012, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/22561606

Di. Wang, et.al., Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling., Nature immunology, 2012, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tespa1<tm1Lrgl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432877

class

http://purl.org/net/cito/citesAsAuthority

• Tespa1<tm1Lrgl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432877

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased regulatory T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0004974B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• abnormal CD8-positive, alpha beta T cell morphology_B2m<tm1Unc>/B2m<tm1Unc>,Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0005010I129129P2OlaHsdC57BL6B2mtm1UncB2mtm1UncTespa1tm1LrglTespa1tm1LrglTespa1tm1LrglB2mtm1Unc
• decreased interferon-gamma secretion_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0008567B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• decreased CD8-positive, alpha-beta T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0008079B6CgTespa1tm1LrglTgTcraTcrb425CbnTespa1tm1LrglTespa1tm1LrglTgTcraTcrb425Cbn0Tespa1tm1LrglTgTcraTcrb425Cbn
• absent CD4-positive, alpha beta T cells_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0003790I129129S2SvPasC57BL6H2Ab1tm1GruH2Ab1tm1GruTespa1tm1LrglTespa1tm1LrglTespa1tm1LrglH2Ab1tm1Gru
• increased T cell proliferation_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0005348B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• decreased CD4-positive, alpha beta T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0008075B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• abnormal T cell differentiation_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0002145B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• decreased T cell proliferation_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0005095B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• decreased T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0005018B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• abnormal T cell differentiation_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0002145B6CgTespa1tm1LrglTgTcraTcrb425CbnTespa1tm1LrglTespa1tm1LrglTgTcraTcrb425Cbn0Tespa1tm1LrglTgTcraTcrb425Cbn
• small thymus medulla_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0013588B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• decreased CD8-positive, alpha-beta T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>,Tg(TcraTcrb)1100Mjb/0
  http://metadb.riken.jp/0008079B6CgTespa1tm1LrglTgTcraTcrb1100MjbTespa1tm1LrglTespa1tm1LrglTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbTespa1tm1Lrgl
• increased memory T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0008049B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• decreased CD4-positive, alpha beta T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>,Tg(TcraTcrb)1100Mjb/0
  http://metadb.riken.jp/0008075B6CgTespa1tm1LrglTgTcraTcrb1100MjbTespa1tm1LrglTespa1tm1LrglTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbTespa1tm1Lrgl
• decreased interleukin-2 secretion_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0008688B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• abnormal thymus morphology_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0000703B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• decreased CD8-positive, alpha-beta T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0008079I129C57BL6DBA2JTespa1tm1LrglTespa1tm1LrglTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboTespa1tm1Lrgl
• decreased CD8-positive, alpha-beta T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0008079B6129Tespa1tm1LrglTespa1tm1LrglTespa1tm1LrglTespa1tm1Lrgl
• abnormal T cell differentiation_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>,Tg(TcraTcrb)1100Mjb/0
  http://metadb.riken.jp/0002145B6CgTespa1tm1LrglTgTcraTcrb1100MjbTespa1tm1LrglTespa1tm1LrglTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbTespa1tm1Lrgl
• decreased CD8-positive, alpha-beta T cell number_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>
  http://metadb.riken.jp/0008079I129129S2SvPasC57BL6H2Ab1tm1GruH2Ab1tm1GruTespa1tm1LrglTespa1tm1LrglTespa1tm1LrglH2Ab1tm1Gru
• decreased CD4-positive, alpha beta T cell number_Tespa1<tm1Lrgl>/Tespa1<tm1Lrgl>,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0008075B6CgTespa1tm1LrglTgTcraTcrb425CbnTespa1tm1LrglTespa1tm1LrglTgTcraTcrb425Cbn0Tespa1tm1LrglTgTcraTcrb425Cbn