Frank. Thiele, et.al., Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms., Human molecular genetics, 2012, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/22589248

Frank. Thiele, et.al., Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms., Human molecular genetics, 2012, 21

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardium layer morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0005329C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• postnatal lethality, incomplete penetrance_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0011086C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• pulmonary alveolar hemorrhage_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0010909C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• decreased ventricle muscle contractility_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0005598C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• rib fractures_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0004675C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• increased QRS amplitude_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0010634C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• abnormal blood vessel morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001614C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• lung inflammation_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001861C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• decreased body weight_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001262C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• abnormal heart electrocardiography waveform feature_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0010508C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• abnormal endoplasmic reticulum morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0009378C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• abnormal cell morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000358C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• heart right ventricle hypertrophy_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000276C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• abnormal blood gas level_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0002329C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• abnormal cardiovascular system physiology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001544C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1
• abnormal heart septum morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0006113C3HeBFeJCol1a1Aga2Col1a1Aga2Col1a1Col1a1Aga2Col1a1