Baichun. Jiang, et.al., Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/22606329

Baichun. Jiang, et.al., Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development., PloS one, 2012, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cul4b<tm1Yxg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5500946
• Cul4b<tm1.1Yxg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5500947

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• pallor_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0003717I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• increased embryonic tissue cell apoptosis_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0013504I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• fetal growth retardation_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0004201I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• lethality throughout fetal growth and development, incomplete penetrance_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0011109I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• lethality during fetal growth through weaning, incomplete penetrance_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0011112I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• abnormal embryonic tissue morphology_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0002085I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• abnormal extraembryonic tissue morphology_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0002086I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• abnormal placenta labyrinth morphology_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0001716I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• embryonic growth retardation_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0003984I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• decreased embryo size_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0001698I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• pale placenta_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0004266I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• decreased fetal size_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0004200I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• no abnormal phenotype detected_Cul4b<tm1Yxg>/Y
  http://metadb.riken.jp/0002169I129X1SvJCul4btm1YxgYCul4btm1Yxg
• disorganized extraembryonic tissue_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0002582I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• postnatal growth retardation_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0001732I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• disorganized placental labyrinth_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0011527I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• decreased cell proliferation_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0000352I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• decreased embryo size_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0001698I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• decreased body size_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0001265I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• abnormal visceral yolk sac morphology_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0001718I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• decreased body weight_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0001262I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• abnormal dosage compensation, by inactivation of X chromosome_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0010382I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• embryonic lethality during organogenesis, complete penetrance_Cul4b<tm1.1Yxg>/Y
  http://metadb.riken.jp/0011098I129X1SvJFVBNCul4btm11YxgYCul4btm11Yxg
• small placenta_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0004259I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• embryonic growth retardation_Cul4b<tm1.1Yxg>/Cul4b<+>
  http://metadb.riken.jp/0003984I129X1SvJFVBNCul4btm11YxgCul4bCul4btm11YxgCul4b
• no abnormal phenotype detected_Cul4b<tm1Yxg>/Cul4b<tm1Yxg>
  http://metadb.riken.jp/0002169I129X1SvJCul4btm1YxgCul4btm1YxgCul4btm1Yxg

class

http://purl.org/net/cito/citesAsAuthority

• Cul4b<tm1Yxg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5500946
• Cul4b<tm1.1Yxg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5500947