Mallika. Singh, et.al., Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models., The Journal of pathology, 2012, 227

http://rdf.ncbi.nlm.nih.gov/pubmed/22611036

Mallika. Singh, et.al., Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models., The Journal of pathology, 2012, 227

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm1Lejo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5641750

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pancreas morphology_Tg(Ins2-Tag*,-flpe)#Gne/0
  http://metadb.riken.jp/0001944IC57BL6JTgIns2TagflpeGne0TgIns2TagflpeGne
• increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Lejo>/Trp53<tm1Lejo>
  http://metadb.riken.jp/0002027I129S4SvJaeKrastm4TyjKrasTrp53tm1LejoTrp53tm1LejoKrasKrastm4TyjTrp53tm1Lejo
• increased insulinoma incidence_Tg(Ins2-Tag*,-flpe)#Gne/0
  http://metadb.riken.jp/0003364IC57BL6JTgIns2TagflpeGne0TgIns2TagflpeGne
• increased lung small cell carcinoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Lejo>/Trp53<tm1Lejo>
  http://metadb.riken.jp/0008715I129Rb1tm2BrnRb1tm2BrnTrp53tm1LejoTrp53tm1LejoTrp53tm1LejoRb1tm2Brn
• increased lung non-small cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Lejo>/Trp53<tm1Lejo>
  http://metadb.riken.jp/0008716I129S4SvJaeKrastm4TyjKrasTrp53tm1LejoTrp53tm1LejoKrasKrastm4TyjTrp53tm1Lejo
• internal hemorrhage_Tg(Ins2-Tag*,-flpe)#Gne/0
  http://metadb.riken.jp/0001634IC57BL6JTgIns2TagflpeGne0TgIns2TagflpeGne
• abnormal lung morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Lejo>/Trp53<tm1Lejo>
  http://metadb.riken.jp/0001175I129Rb1tm2BrnRb1tm2BrnTrp53tm1LejoTrp53tm1LejoTrp53tm1LejoRb1tm2Brn
• premature death_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Lejo>/Trp53<tm1Lejo>
  http://metadb.riken.jp/0002083I129Rb1tm2BrnRb1tm2BrnTrp53tm1LejoTrp53tm1LejoTrp53tm1LejoRb1tm2Brn
• increased pancreas tumor incidence_Tg(Ins2-Tag*,-flpe)#Gne/0
  http://metadb.riken.jp/0009153IC57BL6JTgIns2TagflpeGne0TgIns2TagflpeGne
• increased pancreatic islet cell carcinoma incidence_Tg(Ins2-Tag*,-flpe)#Gne/0
  http://metadb.riken.jp/0010348IC57BL6JTgIns2TagflpeGne0TgIns2TagflpeGne
• premature death_Tg(Ins2-Tag*,-flpe)#Gne/0
  http://metadb.riken.jp/0002083IC57BL6JTgIns2TagflpeGne0TgIns2TagflpeGne
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129S4SvJaeC57BL6CBACdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKrasCdkn2atm4Rdp

class

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm1Lejo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5641750