Ting. Zhao, et.al., Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes., The Journal of biological chemistry, 2012, 287

http://rdf.ncbi.nlm.nih.gov/pubmed/22619176

Ting. Zhao, et.al., Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes., The Journal of biological chemistry, 2012, 287

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mfn2<tm1.1Mzhe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5445195

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mitochondrion morphology_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>
  http://metadb.riken.jp/0006035I129S1Sv129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMfn2tm11Mzhe
• abnormal cellular respiration_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0010954I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• abnormal autophagy_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008260I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• abnormal myocardial fiber physiology_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004215I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• decreased ventricle muscle contractility_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005598I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• increased response of heart to induced stress_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004485I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• lipofuscinosis_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008842I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• abnormal mitochondrion morphology_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0006035I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• increased fetal cardiomyocyte apoptosis_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0011392I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc
• abnormal myocardial fiber morphology_Mfn2<tm1.1Mzhe>/Mfn2<tm1.1Mzhe>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0000278I129S1Sv129S4SvJae129X1SvJC57BL6JMfn2tm11MzheMfn2tm11MzheMyl2tm1creKrcMyl2Myl2Mfn2tm11MzheMyl2tm1creKrc

class

http://purl.org/net/cito/citesAsAuthority

• Mfn2<tm1.1Mzhe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5445195