Tongyuan. Li, et.al., Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence., Cell, 2012, 149

http://rdf.ncbi.nlm.nih.gov/pubmed/22682249

Tongyuan. Li, et.al., Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence., Cell, 2012, 149

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm2.1Wgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431730
• Trp53<tm1.1Wgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431727

class

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm2.1Wgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431730
• Trp53<tm1.1Wgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431727

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• delayed cellular replicative senescence_Trp53<tm2.1Wgu>/Trp53<tm2.1Wgu>
  http://metadb.riken.jp/0008009I129S6SvEvTacC57BL6Trp53tm21WguTrp53tm21WguTrp53tm21Wgu
• increased fibroblast proliferation_Trp53<tm1.1Wgu>/Trp53<tm1.1Wgu>
  http://metadb.riken.jp/0011703I129S6SvEvTacC57BL6Trp53tm11WguTrp53tm11WguTrp53tm11Wgu
• enhanced cellular glucose import_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0003927I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• delayed cellular replicative senescence_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0008009I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• increased fibroblast proliferation_Trp53<tm2.1Wgu>/Trp53<tm2.1Wgu>
  http://metadb.riken.jp/0011703I129S6SvEvTacC57BL6Trp53tm21WguTrp53tm21WguTrp53tm21Wgu
• increased tumor incidence_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002020I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• increased fibroblast proliferation_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0011703I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• abnormal cell physiology_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0005621I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• decreased cellular sensitivity to gamma-irradiation_Trp53<tm1.1Wgu>/Trp53<tm1.1Wgu>
  http://metadb.riken.jp/0003207I129S6SvEvTacC57BL6Trp53tm11WguTrp53tm11WguTrp53tm11Wgu
• premature death_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002083I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• oxidative stress_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0003674I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• abnormal cell cycle_Trp53<tm2.1Wgu>/Trp53<tm2.1Wgu>
  http://metadb.riken.jp/0003077I129S6SvEvTacC57BL6Trp53tm21WguTrp53tm21WguTrp53tm21Wgu
• decreased thymocyte apoptosis_Trp53<tm2.1Wgu>/Trp53<tm2.1Wgu>
  http://metadb.riken.jp/0009542I129S6SvEvTacC57BL6Trp53tm21WguTrp53tm21WguTrp53tm21Wgu
• decreased thymocyte apoptosis_Trp53<tm1.1Wgu>/Trp53<tm1.1Wgu>
  http://metadb.riken.jp/0009542I129S6SvEvTacC57BL6Trp53tm11WguTrp53tm11WguTrp53tm11Wgu
• decreased thymocyte apoptosis_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0009542I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enhanced cellular glucose import in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010229
• increased fibroblast proliferation in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010238
• delayed cellular replicative senescence in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010234
• decreased thymocyte apoptosis in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010236
• abnormal cell physiology in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010233
• oxidative stress in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010227