Ivan. Grskovic, et.al., Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2012, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/22692895

Ivan. Grskovic, et.al., Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2012, 27

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal femur morphology_Anxa5<tm1Epo>/Anxa5<tm1Epo>,Anxa6<tm1Moss>/Anxa6<tm1Moss>,Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0000559I129P2OlaHsd129SSvEvC57BL6Anxa5tm1EpoAnxa5tm1EpoAnxa6tm1MossAnxa6tm1MossCol10a1tm1KsecCol10a1tm1KsecAnxa6tm1MossCol10a1tm1KsecAnxa5tm1Epo
• abnormal femur morphology_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0000559I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• decreased interleukin-2 secretion_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008688I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• decreased interleukin-4 secretion_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008700I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• increased interleukin-4 secretion_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008699I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• increased T-helper cell number_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0013763I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• increased B cell number_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0005014I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• decreased bone mineral density of femur_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0020010I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• increased B cell number_Anxa5<tm1Epo>/Anxa5<tm1Epo>,Anxa6<tm1Moss>/Anxa6<tm1Moss>
  http://metadb.riken.jp/0005014I129P2OlaHsdC57BL6Anxa5tm1EpoAnxa5tm1EpoAnxa6tm1MossAnxa6tm1MossAnxa5tm1EpoAnxa6tm1Moss
• decreased bone mineral content_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0010124I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• increased T-helper cell number_Anxa5<tm1Epo>/Anxa5<tm1Epo>,Anxa6<tm1Moss>/Anxa6<tm1Moss>,Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0013763I129P2OlaHsd129SSvEvC57BL6Anxa5tm1EpoAnxa5tm1EpoAnxa6tm1MossAnxa6tm1MossCol10a1tm1KsecCol10a1tm1KsecAnxa6tm1MossCol10a1tm1KsecAnxa5tm1Epo
• increased width of hypertrophic chondrocyte zone_Anxa5<tm1Epo>/Anxa5<tm1Epo>,Anxa6<tm1Moss>/Anxa6<tm1Moss>,Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0003408I129P2OlaHsd129SSvEvC57BL6Anxa5tm1EpoAnxa5tm1EpoAnxa6tm1MossAnxa6tm1MossCol10a1tm1KsecCol10a1tm1KsecAnxa6tm1MossCol10a1tm1KsecAnxa5tm1Epo
• decreased dendritic cell number_Anxa5<tm1Epo>/Anxa5<tm1Epo>,Anxa6<tm1Moss>/Anxa6<tm1Moss>,Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008127I129P2OlaHsd129SSvEvC57BL6Anxa5tm1EpoAnxa5tm1EpoAnxa6tm1MossAnxa6tm1MossCol10a1tm1KsecCol10a1tm1KsecAnxa6tm1MossCol10a1tm1KsecAnxa5tm1Epo
• decreased interleukin-17 secretion_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008682I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• increased B cell number_Anxa5<tm1Epo>/Anxa5<tm1Epo>,Anxa6<tm1Moss>/Anxa6<tm1Moss>,Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0005014I129P2OlaHsd129SSvEvC57BL6Anxa5tm1EpoAnxa5tm1EpoAnxa6tm1MossAnxa6tm1MossCol10a1tm1KsecCol10a1tm1KsecAnxa6tm1MossCol10a1tm1KsecAnxa5tm1Epo
• decreased dendritic cell number_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008127I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• decreased dendritic cell number_Anxa5<tm1Epo>/Anxa5<tm1Epo>,Anxa6<tm1Moss>/Anxa6<tm1Moss>
  http://metadb.riken.jp/0008127I129P2OlaHsdC57BL6Anxa5tm1EpoAnxa5tm1EpoAnxa6tm1MossAnxa6tm1MossAnxa5tm1EpoAnxa6tm1Moss
• abnormal T-helper 2 cell differentiation_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008092I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• decreased interleukin-10 secretion_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0008661I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec
• increased width of hypertrophic chondrocyte zone_Col10a1<tm1Ksec>/Col10a1<tm1Ksec>
  http://metadb.riken.jp/0003408I129SSvEvC57BL6Col10a1tm1KsecCol10a1tm1KsecCol10a1tm1Ksec