Matthieu. Raveau, et.al., The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model., PLoS genetics, 2012, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/22693452

Matthieu. Raveau, et.al., The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model., PLoS genetics, 2012, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• App<tm1Yah>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431210
• Del(16App-Runx1)5Yah
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431211

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart morphology_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0000266IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• prolonged QT interval_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0003233IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• prolonged PR interval_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0003896IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• abnormal QRS complex_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0003898IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• retroesophageal right subclavian artery_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0004160IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• decreased heart rate_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0005333IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
他9件を見る
• prolonged QRS complex duration_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0010392IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• decreased QRS amplitude_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0010394IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• ventricular septal defect_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0010402IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• prolonged RR interval_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0010506IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• abnormal heart electrocardiography waveform feature_Del(16App-Runx1)5Yah/Ts(17<16>)65Dn
  http://metadb.riken.jp/0010508IBALBcC3HC57BL6DBA2JDel16AppRunx15YahTs171665DnDel16AppRunx15YahTs171665Dn
• abnormal heart electrocardiography waveform feature_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0010508IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• decreased P wave amplitude_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0010509IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• postnatal lethality, incomplete penetrance_Ts(17<16>)65Dn/0
  http://metadb.riken.jp/0011086IC3HHeHC3HHeSnC57BL6EiC57BL6JDBA2JTs171665Dn0Ts171665Dn
• perinatal lethality, incomplete penetrance_Del(16App-Runx1)5Yah/+
  http://metadb.riken.jp/0011090I129S1Sv129X1SvJBALBcC57BL6Del16AppRunx15YahDel16AppRunx15Yah

class

http://purl.org/net/cito/citesAsAuthority

• App<tm1Yah>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431210
• Del(16App-Runx1)5Yah
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431211