Michael J. Schmeisser, et.al., Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2., Nature, 2012, 486

http://rdf.ncbi.nlm.nih.gov/pubmed/22699619

Michael J. Schmeisser, et.al., Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2., Nature, 2012, 486

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Shank3<tm1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435699
• Shank2<tm1.1Tmb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435698
• Shank2<tm1Tmb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435697
• Shank3<tm1.1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435700

class

http://purl.org/net/cito/citesAsAuthority

• Shank3<tm1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435699
• Shank2<tm1.1Tmb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435698
• Shank2<tm1Tmb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435697
• Shank3<tm1.1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435700

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal dendritic spine morphology_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0009936B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• limb grasping_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001513B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• increased grooming behavior_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001441B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• improved righting response_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0002863B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• decreased body weight_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001262B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• abnormal response to novelty_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0003107B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• increased anxiety-related response_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001363B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• abnormal miniature excitatory postsynaptic currents_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0004753B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• increased stereotypic behavior_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001409B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• skin lesions_Shank3<tm1.1Geno>/Shank3<tm1.1Geno>
  http://metadb.riken.jp/0001212IC57BL6Shank3tm11GenoShank3tm11GenoShank3tm11Geno
• abnormal excitatory postsynaptic potential_Shank2<tm1.1Tmb>/Shank2<+>
  http://metadb.riken.jp/0002912B6129Shank2tm11TmbShank2tm11TmbShank2Shank2Shank2tm11Tmb
• enhanced long term potentiation_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0003008B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• abnormal social investigation_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001360B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• abnormal motor capabilities/coordination/movement_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0002066B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• hyperactivity_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001399B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• impaired righting response_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001523B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• increased anxiety-related response_Shank2<tm1.1Tmb>/Shank2<+>
  http://metadb.riken.jp/0001363B6129Shank2tm11TmbShank2tm11TmbShank2Shank2Shank2tm11Tmb
• abnormal sexual interaction_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0002566B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• hyperactivity_Shank2<tm1.1Tmb>/Shank2<+>
  http://metadb.riken.jp/0001399B6129Shank2tm11TmbShank2tm11TmbShank2Shank2Shank2tm11Tmb
• postnatal lethality, incomplete penetrance_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0011086B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• abnormal vocalization_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0001529B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• abnormal excitatory postsynaptic potential_Shank2<tm1.1Tmb>/Shank2<tm1.1Tmb>
  http://metadb.riken.jp/0002912B6129Shank2tm11TmbShank2tm11TmbShank2tm11TmbShank2tm11Tmb
• postnatal lethality, incomplete penetrance_Shank2<tm1.1Tmb>/Shank2<+>
  http://metadb.riken.jp/0011086B6129Shank2tm11TmbShank2tm11TmbShank2Shank2Shank2tm11Tmb