Deirdre M. Fuller, et.al., Regulation of RasGRP1 function in T cell development and activation by its unique tail domain., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/22719950

Deirdre M. Fuller, et.al., Regulation of RasGRP1 function in T cell development and activation by its unique tail domain., PloS one, 2012, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5694744

class

http://purl.org/net/cito/citesAsAuthority

• Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5694744

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased double-positive T cell number_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0005091IC57BL6JDBA2JRasgrp1tm11WzRasgrp1tm11WzTgTcraHYTcrbHY71VboRasgrp1tm11WzTgTcraHYTcrbHY71Vbo
• increased spleen weight_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0004952B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal CD8-positive, alpha-beta T cell differentiation_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0008080B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• increased CD4-positive, alpha-beta memory T cell number_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0010835B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• decreased single-positive T cell number_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0008083B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal immune system organ morphology_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0002722B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal CD4-positive T cell differentiation_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0008076B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• increased single-positive T cell number_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0008082B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal immune system cell morphology_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0000716B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal immune system physiology_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0001790B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• increased autoantibody level_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0003725B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• decreased single-positive T cell number_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0008083IC57BL6JDBA2JRasgrp1tm11WzRasgrp1tm11WzTgTcraHYTcrbHY71VboRasgrp1tm11WzTgTcraHYTcrbHY71Vbo
• increased IgG1 level_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0008499B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal immunoglobulin level_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0002490B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• increased IgE level_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0002497B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal T cell differentiation_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0002145B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• enlarged spleen_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0000691B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz
• abnormal CD4-positive T cell differentiation_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>,Tg(TcraTcrb)425Cbn/?
  http://metadb.riken.jp/0008076IC57BL6BALBcRasgrp1tm11WzRasgrp1tm11WzTgTcraTcrb425CbnTgTcraTcrb425CbnRasgrp1tm11Wz
• decreased T cell proliferation_Rasgrp1<tm1.1Wz>/Rasgrp1<tm1.1Wz>
  http://metadb.riken.jp/0005095B6CgRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11WzRasgrp1tm11Wz