Yaming. Wang, et.al., IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia., Nature immunology, 2012, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/22729249

Yaming. Wang, et.al., IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia., Nature immunology, 2012, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5438224
• Il34<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5438225

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal microglial cell morphology_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000136IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• decreased dendritic cell number_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008127IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• decreased interferon-gamma secretion_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008567IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• decreased susceptibility to type IV hypersensitivity reaction_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0005616IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• decreased Langerhans cell number_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008119IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• increased susceptibility to viral infection_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002418IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• increased neuron apoptosis_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003203IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• decreased susceptibility to fungal infection_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0005398IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• increased susceptibility to viral infection induced morbidity/mortality_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009791IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• lymph node hypoplasia_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008101IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi
• absent Langerhans cell_Il34<tm1b(EUCOMM)Wtsi>/Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008118IBALBcJC57BL6NIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsiIl34tm1bEUCOMMWtsi

class

http://purl.org/net/cito/citesAsAuthority

• Il34<tm1b(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5438224
• Il34<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5438225