Jim. Geiser, et.al., A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity., PLoS genetics, 2012, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/22737083

Jim. Geiser, et.al., A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity., PLoS genetics, 2012, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Slc39a4<tm2Gka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5438020

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mineral homeostasis_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0005636I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• abnormal copper level_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0003952I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• abnormal small intestinal villus morphology_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008108I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• postnatal growth retardation_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• abnormal small intestinal crypt cell proliferation_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0010157I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• abnormal zinc homeostasis_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0009615I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• abnormal small intestine crypts of Lieberkuhn morphology_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0004841I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• decreased intestine copper level_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0010248I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• abnormal Paneth cell morphology_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0004843I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• decreased bone mass_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0004016I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• abnormal liver morphology_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0000598I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• decreased liver copper level_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0003067I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• increased liver copper level_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0003066I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• lethality at weaning, complete penetrance_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0011083I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• premature death_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• weight loss_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0001263I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• increased liver iron level_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008807I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• decreased intestinal iron level_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0020385I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka
• decreased muscle weight_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0004232I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka

class

http://purl.org/net/cito/citesAsAuthority

• Slc39a4<tm2Gka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5438020