Carrie N. Arnold, et.al., A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/22761313

Carrie N. Arnold, et.al., A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nfkbid<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428994
• Pik3ap1<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5429067
• Ruvbl2<M1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428996
• Rag1<m2Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5429068
• Zeb1<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428990

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased IgG1 level_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008495IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased T cell number_Dock2<m1Btlr>/Dock2<m1Btlr>
  http://metadb.riken.jp/0005018IC57BL6JDock2m1BtlrDock2m1BtlrDock2m1Btlr
• decreased IgG level_Nfkbid<tm1a(EUCOMM)Wtsi>/Nfkbid<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001805IC57BL6NNfkbidtm1aEUCOMMWtsiNfkbidtm1aEUCOMMWtsiNfkbidtm1aEUCOMMWtsi
• abnormal class switch recombination_Cd40lg<m1Btlr>/Cd40lg<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JCd40lgm1BtlrCd40lgm1BtlrCd40lgm1Btlr
• decreased B-1 B cell number_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0004978IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• belly spot_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0000373IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• abnormal class switch recombination_Prkdc<m1Btlr>/Prkdc<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JPrkdcm1BtlrPrkdcm1BtlrPrkdcm1Btlr
• abnormal class switch recombination_Nfkbid<tm1a(EUCOMM)Wtsi>/Nfkbid<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0004816IC57BL6NNfkbidtm1aEUCOMMWtsiNfkbidtm1aEUCOMMWtsiNfkbidtm1aEUCOMMWtsi
• abnormal class switch recombination_Map3k14<m1Btlr>/Map3k14<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JMap3k14m1BtlrMap3k14m1BtlrMap3k14m1Btlr
• decreased B-1b cell number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008170IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased IgM level_Plcg2<m1Btlr>/Plcg2<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JPlcg2m1BtlrPlcg2m1BtlrPlcg2m1Btlr
• decreased B cell number_Rag1<m2Btlr>/Rag1<m2Btlr>
  http://metadb.riken.jp/0005017IC57BL6JRag1m2BtlrRag1m2BtlrRag1m2Btlr
• decreased IgG level_Zap70<m1Btlr>/Zap70<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JZap70m1BtlrZap70m1BtlrZap70m1Btlr
• abnormal B cell differentiation_Cd22<m1Btlr>/Cd22<m1Btlr>
  http://metadb.riken.jp/0002144IC57BL6JCd22m1BtlrCd22m1BtlrCd22m1Btlr
• decreased IgG level_Map3k14<m1Btlr>/Map3k14<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JMap3k14m1BtlrMap3k14m1BtlrMap3k14m1Btlr
• arrested B cell differentiation_Blnk<m1Btlr>/Blnk<m1Btlr>
  http://metadb.riken.jp/0001802IC57BL6JBlnkm1BtlrBlnkm1BtlrBlnkm1Btlr
• abnormal class switch recombination_Cd3e<m1Btlr>/Cd3e<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JCd3em1BtlrCd3em1BtlrCd3em1Btlr
• decreased IgG level_Cd40lg<m1Btlr>/Cd40lg<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JCd40lgm1BtlrCd40lgm1BtlrCd40lgm1Btlr
• abnormal class switch recombination_Rag1<m2Btlr>/Rag1<m2Btlr>
  http://metadb.riken.jp/0004816IC57BL6JRag1m2BtlrRag1m2BtlrRag1m2Btlr
• decreased B cell number_Prkdc<m1Btlr>/Prkdc<m1Btlr>
  http://metadb.riken.jp/0005017IC57BL6JPrkdcm1BtlrPrkdcm1BtlrPrkdcm1Btlr
• abnormal class switch recombination_Zap70<m1Btlr>/Zap70<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JZap70m1BtlrZap70m1BtlrZap70m1Btlr
• increased single-positive T cell number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008082IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased IgM level_Cd79a<m1Btlr>/Cd79a<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JCd79am1BtlrCd79am1BtlrCd79am1Btlr
• arrested B cell differentiation_Map3k14<m1Btlr>/Map3k14<m1Btlr>
  http://metadb.riken.jp/0001802IC57BL6JMap3k14m1BtlrMap3k14m1BtlrMap3k14m1Btlr
• decreased B cell proliferation_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0005093IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• increased thymocyte number_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0000714IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• decreased IgM level_Prkdc<m1Btlr>/Prkdc<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JPrkdcm1BtlrPrkdcm1BtlrPrkdcm1Btlr
• decreased B cell number_Atp11c<m1Btlr>/Atp11c<m1Btlr>
  http://metadb.riken.jp/0005017IC57BL6JAtp11cm1BtlrAtp11cm1BtlrAtp11cm1Btlr
• decreased IgM level_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased B cell number_Atp11c<m2Btlr>/Atp11c<m2Btlr>
  http://metadb.riken.jp/0005017IC57BL6JAtp11cm2BtlrAtp11cm2BtlrAtp11cm2Btlr
• decreased IgG level_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0001805IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• abnormal class switch recombination_Cd40lg<m1Btlr>/Y
  http://metadb.riken.jp/0004816IC57BL6JCd40lgm1BtlrYCd40lgm1Btlr
• decreased double-positive T cell number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0005092IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• abnormal B cell differentiation_Plcg2<m1Btlr>/Plcg2<m1Btlr>
  http://metadb.riken.jp/0002144IC57BL6JPlcg2m1BtlrPlcg2m1BtlrPlcg2m1Btlr
• absent marginal zone B cells_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008183IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• abnormal class switch recombination_Irf4<m1Btlr>/Irf4<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JIrf4m1BtlrIrf4m1BtlrIrf4m1Btlr
• abnormal humoral immune response_Dock2<m2Btlr>/Dock2<m2Btlr>
  http://metadb.riken.jp/0001800IC57BL6JDock2m2BtlrDock2m2BtlrDock2m2Btlr
• decreased IgM level_Rag1<m2Btlr>/Rag1<m2Btlr>
  http://metadb.riken.jp/0001806IC57BL6JRag1m2BtlrRag1m2BtlrRag1m2Btlr
• decreased IgM level_Prkcb<M1Btlr>/Prkcb<M1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JPrkcbM1BtlrPrkcbM1BtlrPrkcbM1Btlr
• decreased CD8-positive, alpha-beta T cell number_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0008079IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• decreased IgG level_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased IgG level_Dock2<m1Btlr>/Dock2<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JDock2m1BtlrDock2m1BtlrDock2m1Btlr
• decreased germinal center B cell number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008178IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased IgG level_Prkdc<m1Btlr>/Prkdc<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JPrkdcm1BtlrPrkdcm1BtlrPrkdcm1Btlr
• abnormal class switch recombination_Cd79a<m1Btlr>/Cd79a<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JCd79am1BtlrCd79am1BtlrCd79am1Btlr
• decreased IgG1 level_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0008495IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• decreased IgG level_Rag1<m2Btlr>/Rag1<m2Btlr>
  http://metadb.riken.jp/0001805IC57BL6JRag1m2BtlrRag1m2BtlrRag1m2Btlr
• abnormal class switch recombination_Dock2<m1Btlr>/Dock2<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JDock2m1BtlrDock2m1BtlrDock2m1Btlr
• increased B cell apoptosis_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0008782IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased IgM level_Nfkbid<tm1a(EUCOMM)Wtsi>/Nfkbid<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001806IC57BL6NNfkbidtm1aEUCOMMWtsiNfkbidtm1aEUCOMMWtsiNfkbidtm1aEUCOMMWtsi
• decreased B-1a cell number_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0008168IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased B-1 B cell number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0004978IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased T cell number_Dock2<m2Btlr>/Dock2<m2Btlr>
  http://metadb.riken.jp/0005018IC57BL6JDock2m2BtlrDock2m2BtlrDock2m2Btlr
• decreased IgM level_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased B cell number_Dock2<m1Btlr>/Dock2<m1Btlr>
  http://metadb.riken.jp/0005017IC57BL6JDock2m1BtlrDock2m1BtlrDock2m1Btlr
• absent marginal zone B cells_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0008183IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased IgG3 level_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0008498IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased T cell number_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0005018IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• abnormal class switch recombination_Dock2<m2Btlr>/Dock2<m2Btlr>
  http://metadb.riken.jp/0004816IC57BL6JDock2m2BtlrDock2m2BtlrDock2m2Btlr
• increased thymocyte number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0000714IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased IgG level_Cd40lg<m1Btlr>/Y
  http://metadb.riken.jp/0001805IC57BL6JCd40lgm1BtlrYCd40lgm1Btlr
• arrested B cell differentiation_Pik3ap1<m1Btlr>/Pik3ap1<m1Btlr>
  http://metadb.riken.jp/0001802IC57BL6JPik3ap1m1BtlrPik3ap1m1BtlrPik3ap1m1Btlr
• abnormal memory B cell physiology_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008194IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• lethality, complete penetrance_Ruvbl2<M1Btlr>/Ruvbl2<M1Btlr>
  http://metadb.riken.jp/0011400IC57BL6JRuvbl2M1BtlrRuvbl2M1BtlrRuvbl2M1Btlr
• decreased T cell number_Zap70<m1Btlr>/Zap70<m1Btlr>
  http://metadb.riken.jp/0005018IC57BL6JZap70m1BtlrZap70m1BtlrZap70m1Btlr
• decreased B cell number_Atp11c<m1Btlr>/Y
  http://metadb.riken.jp/0005017IC57BL6JAtp11cm1BtlrYAtp11cm1Btlr
• decreased T cell number_Rag1<m2Btlr>/Rag1<m2Btlr>
  http://metadb.riken.jp/0005018IC57BL6JRag1m2BtlrRag1m2BtlrRag1m2Btlr
• abnormal class switch recombination_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• abnormal class switch recombination_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0004816IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased IgM level_Blnk<m1Btlr>/Blnk<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JBlnkm1BtlrBlnkm1BtlrBlnkm1Btlr
• abnormal B cell differentiation_Dock2<m2Btlr>/Dock2<m2Btlr>
  http://metadb.riken.jp/0002144IC57BL6JDock2m2BtlrDock2m2BtlrDock2m2Btlr
• decreased IgM level_Cd22<m1Btlr>/Cd22<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JCd22m1BtlrCd22m1BtlrCd22m1Btlr
• decreased B cell proliferation_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0005093IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased NK cell number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008045IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased B cell number_Cd79a<m1Btlr>/Cd79a<m1Btlr>
  http://metadb.riken.jp/0005017IC57BL6JCd79am1BtlrCd79am1BtlrCd79am1Btlr
• abnormal B cell differentiation_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0002144IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased B-1a cell number_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0008168IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr
• decreased IgG1 level_Nfkbid<m1Btlr>/Nfkbid<m1Btlr>
  http://metadb.riken.jp/0008495IC57BL6JNfkbidm1BtlrNfkbidm1BtlrNfkbidm1Btlr
• decreased CD4-positive, alpha beta T cell number_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0008075IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• decreased IgG level_Irf4<m1Btlr>/Irf4<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JIrf4m1BtlrIrf4m1BtlrIrf4m1Btlr
• decreased IgM level_Pik3ap1<m1Btlr>/Pik3ap1<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JPik3ap1m1BtlrPik3ap1m1BtlrPik3ap1m1Btlr
• decreased double-positive T cell number_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0005092IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• decreased IgM level_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0001806IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• decreased B cell number_Dock2<m2Btlr>/Dock2<m2Btlr>
  http://metadb.riken.jp/0005017IC57BL6JDock2m2BtlrDock2m2BtlrDock2m2Btlr
• decreased IgG level_Dock2<m2Btlr>/Dock2<m2Btlr>
  http://metadb.riken.jp/0001805IC57BL6JDock2m2BtlrDock2m2BtlrDock2m2Btlr
• decreased IgG level_Cd79a<m1Btlr>/Cd79a<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JCd79am1BtlrCd79am1BtlrCd79am1Btlr
• abnormal class switch recombination_Ruvbl2<M1Btlr>/Ruvbl2<+>
  http://metadb.riken.jp/0004816IC57BL6JRuvbl2M1BtlrRuvbl2Ruvbl2M1BtlrRuvbl2
• decreased B cell number_Atp11c<m2Btlr>/Y
  http://metadb.riken.jp/0005017IC57BL6JAtp11cm2BtlrYAtp11cm2Btlr
• decreased IgM level_Irf4<m1Btlr>/Irf4<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JIrf4m1BtlrIrf4m1BtlrIrf4m1Btlr
• decreased IgG level_Zeb1<m1Btlr>/Zeb1<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JZeb1m1BtlrZeb1m1BtlrZeb1m1Btlr

class

http://purl.org/net/cito/citesAsAuthority

• Nfkbid<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428994
• Pik3ap1<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5429067
• Ruvbl2<M1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428996
• Rag1<m2Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5429068
• Zeb1<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428990