Peter T. Tsai, et.al., Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice., Nature, 2012, 488

http://rdf.ncbi.nlm.nih.gov/pubmed/22763451

Peter T. Tsai, et.al., Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice., Nature, 2012, 488

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal learning/memory/conditioning_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0002063I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• ataxia_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001393I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal Purkinje cell morphology_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0000877I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal Purkinje cell dendrite morphology_Tsc1<tm1Djk>/Tsc1<+>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0008572I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1TgPcp2cre2Mpin0Tsc1TgPcp2cre2MpinTsc1tm1Djk
• increased grooming behavior_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001441I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• excessive vocalization_Tsc1<tm1Djk>/Tsc1<+>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0013140I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1TgPcp2cre2Mpin0Tsc1TgPcp2cre2MpinTsc1tm1Djk
• excessive vocalization_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0013140I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal social investigation_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001360I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal cerebellar Purkinje cell layer_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0000875I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal social investigation_Tsc1<tm1Djk>/Tsc1<+>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001360I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1TgPcp2cre2Mpin0Tsc1TgPcp2cre2MpinTsc1tm1Djk
• impaired coordination_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001405I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• decreased Purkinje cell number_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0000880I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal Purkinje cell dendrite morphology_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0008572I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal nervous system physiology_Tsc1<tm1Djk>/Tsc1<+>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0003633I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1TgPcp2cre2Mpin0Tsc1TgPcp2cre2MpinTsc1tm1Djk
• abnormal sexual interaction_Tsc1<tm1Djk>/Tsc1<+>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0002566I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1TgPcp2cre2Mpin0Tsc1TgPcp2cre2MpinTsc1tm1Djk
• increased grooming behavior_Tsc1<tm1Djk>/Tsc1<+>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001441I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1TgPcp2cre2Mpin0Tsc1TgPcp2cre2MpinTsc1tm1Djk
• abnormal sexual interaction_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0002566I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• short stride length_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001407I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal nervous system physiology_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0003633I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal response to novel odor_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0003462I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1tm1DjkTgPcp2cre2Mpin0TgPcp2cre2MpinTsc1tm1Djk
• abnormal response to novel odor_Tsc1<tm1Djk>/Tsc1<+>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0003462I129S1Sv129S4SvJae129X1SvJBALBcJC57BL6JTsc1tm1DjkTsc1TgPcp2cre2Mpin0Tsc1TgPcp2cre2MpinTsc1tm1Djk