Hiromitsu. Saito, et.al., Reduced bone morphogenetic protein receptor type 1A signaling in neural-crest-derived cells causes facial dysmorphism., Disease models & mechanisms, 2012, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/22773757

Hiromitsu. Saito, et.al., Reduced bone morphogenetic protein receptor type 1A signaling in neural-crest-derived cells causes facial dysmorphism., Disease models & mechanisms, 2012, 5

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-Bmpr1a*,-lacZ)1Nobs
  http://metadb.riken.jp/db/mgi_rdf/MGI:5473821

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-Bmpr1a*,-lacZ)1Nobs
  http://metadb.riken.jp/db/mgi_rdf/MGI:5473821

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• belly spot_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0000373I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• ocular hypertelorism_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0001300I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• short snout_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0000445I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal head mesenchyme morphology_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0011260I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal craniofacial development_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0003935I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• facial cleft_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0008797I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal nasal septum morphology_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0002239I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• midline facial cleft_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0000108I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• no abnormal phenotype detected_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/Tg(CAG-Bmpr1a*,-lacZ)1Nobs
  http://metadb.riken.jp/0002169B6CgTgCAGBmpr1alacZ1NobsTgCAGBmpr1alacZ1NobsTgCAGBmpr1alacZ1NobsTgCAGBmpr1alacZ1Nobs
• cleft palate_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0000111I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• neonatal lethality, incomplete penetrance_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0011088I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal frontonasal mesenchyme morphology_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0011266I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• small frontal bone_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0004377I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• decreased survivor rate_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0008770I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal facial morphology_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0003743I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal nasal bone morphology_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0000102I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal bone ossification_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0008271I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal fontanelle morphology_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0000084I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal neurocranium morphology_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0000074I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• abnormal suckling behavior_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0001436I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg
• ventricular septal defect_Tg(CAG-Bmpr1a*,-lacZ)1Nobs/0,Tg(Mpz-cre)94Imeg/0
  http://metadb.riken.jp/0010402I129X1SvJC57BL6JTgCAGBmpr1alacZ1Nobs0TgMpzcre94Imeg0TgCAGBmpr1alacZ1NobsTgMpzcre94Imeg