Satoshi. Somekawa, et.al., Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/22783020

Satoshi. Somekawa, et.al., Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tmem100<tm2.1Ysai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432905
• Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432904

class

http://purl.org/net/cito/citesAsAuthority

• Tmem100<tm2.1Ysai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432905
• Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432904

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal blood circulation_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0002128C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal vitelline vasculature morphology_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0003229I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• pericardial effusion_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0005312IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• abnormal trabecula carnea morphology_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0004067I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal visceral yolk sac morphology_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001718IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• embryonic growth retardation_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0003984C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• thin myocardium_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0002652C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal vitelline vascular remodeling_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0004076C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• embryonic lethality during organogenesis, complete penetrance_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal visceral yolk sac morphology_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0001718C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal heart layer morphology_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0010545C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• pericardial effusion_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0005312C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal blood vessel morphology_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001614IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• embryonic lethality during organogenesis, complete penetrance_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0011098C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• enlarged heart_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0000274I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal dorsal aorta morphology_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0004787C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal developmental vascular remodeling_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0009577C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal visceral yolk sac morphology_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0001718I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal trabecula carnea morphology_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0004067C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• poor arterial differentiation_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000262IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• arteriovenous malformation_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0006093C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• poor arterial differentiation_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0000262C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal heart morphology_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0000266I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• embryonic lethality during organogenesis, complete penetrance_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011098IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• abnormal vitelline vasculature morphology_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0003229C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal dorsal aorta morphology_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0004787IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• abnormal heart layer morphology_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0010545I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• embryonic growth retardation_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0003984I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal vitelline vasculature morphology_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003229IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• abnormal aorta morphology_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0000272C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• enlarged heart_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0000274C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• abnormal heart morphology_Tmem100<tm1.1Ysai>/Tmem100<tm1.1Ysai>
  http://metadb.riken.jp/0000266C57BL6Tmem100tm11YsaiTmem100tm11YsaiTmem100tm11YsaiTmem100tm11Ysai
• poor arterial differentiation_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0000262I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• pericardial effusion_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0005312I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal developmental vascular remodeling_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0009577I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• embryonic growth retardation_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003984IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa
• abnormal aorta morphology_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0000272I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal dorsal aorta morphology_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0004787I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal vitelline vascular remodeling_Acvrl1<tm1Dgen>/Acvrl1<tm1Dgen>
  http://metadb.riken.jp/0004076I129P2OlaHsdC57BL6Acvrl1tm1DgenAcvrl1tm1DgenAcvrl1tm1Dgen
• abnormal trabecula carnea morphology_Tmem100<tm1.1Ysai>/Tmem100<tm2.1Ysai>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0004067IC57BL6SJLTmem100tm11YsaiTmem100tm21YsaiTgTekcre1Ywa0Tmem100tm21YsaiTmem100tm11YsaiTgTekcre1Ywa