Peter P. Chen, et.al., Dissociation of structural and functional phenotypes in cardiac myosin-binding protein C conditional knockout mice., Circulation, 2012, 126

http://rdf.ncbi.nlm.nih.gov/pubmed/22829020

Peter P. Chen, et.al., Dissociation of structural and functional phenotypes in cardiac myosin-binding protein C conditional knockout mice., Circulation, 2012, 126

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mybpc3<tm2.1Rmos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523781

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber morphology_Mybpc3<tm2.1Rmos>/Mybpc3<tm2.1Rmos>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0000278I129C57BL6FVBNMybpc3tm21RmosMybpc3tm21RmosA1cfTgMyh6creEsr11Jmk0Mybpc3tm21RmosA1cfTgMyh6creEsr11Jmk
• abnormal heart left ventricle morphology_Mybpc3<tm2.1Rmos>/Mybpc3<tm2.1Rmos>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003921I129C57BL6FVBNMybpc3tm21RmosMybpc3tm21RmosA1cfTgMyh6creEsr11Jmk0Mybpc3tm21RmosA1cfTgMyh6creEsr11Jmk
• decreased ventricle muscle contractility_Mybpc3<tm2.1Rmos>/Mybpc3<tm2.1Rmos>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005598I129C57BL6FVBNMybpc3tm21RmosMybpc3tm21RmosA1cfTgMyh6creEsr11Jmk0Mybpc3tm21RmosA1cfTgMyh6creEsr11Jmk
• enlarged myocardial fiber_Mybpc3<tm2.1Rmos>/Mybpc3<tm2.1Rmos>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0004564I129C57BL6FVBNMybpc3tm21RmosMybpc3tm21RmosA1cfTgMyh6creEsr11Jmk0Mybpc3tm21RmosA1cfTgMyh6creEsr11Jmk
• increased response of heart to induced stress_Mybpc3<tm2.1Rmos>/Mybpc3<tm2.1Rmos>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0004485I129C57BL6FVBNMybpc3tm21RmosMybpc3tm21RmosA1cfTgMyh6creEsr11Jmk0Mybpc3tm21RmosA1cfTgMyh6creEsr11Jmk
• cardiac interstitial fibrosis_Mybpc3<tm2.1Rmos>/Mybpc3<tm2.1Rmos>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005608I129C57BL6FVBNMybpc3tm21RmosMybpc3tm21RmosA1cfTgMyh6creEsr11Jmk0Mybpc3tm21RmosA1cfTgMyh6creEsr11Jmk
• decreased ventricle muscle contractility_Mybpc3<tm1Rmos>/Mybpc3<tm1Rmos>
  http://metadb.riken.jp/0005598I129Mybpc3tm1RmosMybpc3tm1RmosMybpc3tm1Rmos
• dilated heart left ventricle_Mybpc3<tm1Rmos>/Mybpc3<tm1Rmos>
  http://metadb.riken.jp/0002753I129Mybpc3tm1RmosMybpc3tm1RmosMybpc3tm1Rmos
• cardiac fibrosis_Mybpc3<tm2.1Rmos>/Mybpc3<tm2.1Rmos>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003141I129C57BL6FVBNMybpc3tm21RmosMybpc3tm21RmosA1cfTgMyh6creEsr11Jmk0Mybpc3tm21RmosA1cfTgMyh6creEsr11Jmk
• increased response of heart to induced stress_Mybpc3<tm1Rmos>/Mybpc3<tm1Rmos>
  http://metadb.riken.jp/0004485I129Mybpc3tm1RmosMybpc3tm1RmosMybpc3tm1Rmos

class

http://purl.org/net/cito/citesAsAuthority

• Mybpc3<tm2.1Rmos>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523781