Chao. Peng, et.al., Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes., The Journal of biological chemistry, 2012, 287

http://rdf.ncbi.nlm.nih.gov/pubmed/22854957

Chao. Peng, et.al., Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes., The Journal of biological chemistry, 2012, 287

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Vps18<tm1Wtao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431830
• Vps18<tm1.1Wtao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431976

class

http://purl.org/net/cito/citesAsAuthority

• Vps18<tm1Wtao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431830
• Vps18<tm1.1Wtao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431976

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased brain size_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000774I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• abnormal hippocampus morphology_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000807I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• abnormal cerebellum morphology_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000849I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• small cerebellum_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000852I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• decreased Purkinje cell number_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0000880B129Vps18tm11WtaoTgPcp2cre2MpinVps18tm11WtaoVps18tm11WtaoTgPcp2cre2Mpin0TgPcp2cre2MpinVps18tm11Wtao
• decreased body size_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001265I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
他9件を見る
• postnatal growth retardation_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001732I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• neurodegeneration_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002229I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• increased neuron apoptosis_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003203I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• abnormal neuron physiology_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004811I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• abnormal neuronal migration_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006009I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• abnormal autophagy_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008260I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• abnormal hippocampus CA3 region morphology_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008267I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• postnatal lethality, complete penetrance_Vps18<tm1.1Wtao>/Vps18<tm1.1Wtao>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011085I129S4SvJaeSor129S6SvEvTacC57BL6SJLVps18tm11WtaoVps18tm11WtaoTgNescre1Kln0Vps18tm11WtaoTgNescre1Kln
• preweaning lethality, complete penetrance_Vps18<tm1Wtao>/Vps18<tm1Wtao>
  http://metadb.riken.jp/0011100I129S6SvEvTacC57BL6Vps18tm1WtaoVps18tm1WtaoVps18tm1Wtao