T. El Khassawna, et.al., Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia., Bone, 2012, 51

http://rdf.ncbi.nlm.nih.gov/pubmed/22868293

T. El Khassawna, et.al., Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia., Bone, 2012, 51

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased compact bone volume_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0010964I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• decreased bone mineral density_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000063I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• increased osteoid thickness_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0010929I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• increased osteoclast cell number_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0004984I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• abnormal osteoid morphology_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0010924I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• abnormal bone healing_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0002999I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• abnormal cartilage morphology_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000163I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• fragile skeleton_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000061I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• abnormal osteoblast cell number_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0004987I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt
• abnormal endochondral bone ossification_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0008272I129S1Sv129X1SvJC57BL6JC57BL6NSJLJNf1tm1ParNf1tm1ParTgPrrx1cre1Cjt0Nf1tm1ParTgPrrx1cre1Cjt