Wei. Song, et.al., Schizophrenia-like features in transgenic mice overexpressing human HO-1 in the astrocytic compartment., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/22875919

Wei. Song, et.al., Schizophrenia-like features in transgenic mice overexpressing human HO-1 in the astrocytic compartment., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-HMOX1)#Hyms
  http://metadb.riken.jp/db/mgi_rdf/MGI:5462364
• Tg(GFAP-tTA)#Hyms
  http://metadb.riken.jp/db/mgi_rdf/MGI:5462365

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• oxidative stress_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0003674IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal mitochondrion morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0006035IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal mitochondrial crista morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0011635IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal nervous system physiology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0003633IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal astrocyte morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0002182IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• increased brain iron level_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0020365IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal autophagy_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0008260IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal substantia nigra morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0000836IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal hippocampus morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0000807IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• increased serotonin level_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0010069IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• disorganized mitochondrial cristae_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0011636IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal neurite morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0008415IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• increased dopamine level_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0001906IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• hyperactivity_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0001399IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• decreased prepulse inhibition_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0009142IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal striatum morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0004077IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms
• abnormal dentate gyrus morphology_Tg(GFAP-tTA)#Hyms/0,Tg(tetO-HMOX1)#Hyms/0
  http://metadb.riken.jp/0000812IFVBTgGFAPtTAHyms0TgtetOHMOX1Hyms0TgGFAPtTAHymsTgtetOHMOX1Hyms

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-HMOX1)#Hyms
  http://metadb.riken.jp/db/mgi_rdf/MGI:5462364
• Tg(GFAP-tTA)#Hyms
  http://metadb.riken.jp/db/mgi_rdf/MGI:5462365