Hannes. Olauson, et.al., Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism., Journal of the American Society of Nephrology : JASN, 2012, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/22878961

Hannes. Olauson, et.al., Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism., Journal of the American Society of Nephrology : JASN, 2012, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kl<tm1.1Tel>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515327
• Kl<tm1.2Tel>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515329

class

http://purl.org/net/cito/citesAsAuthority

• Kl<tm1.1Tel>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515327
• Kl<tm1.2Tel>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515329

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• kidney cortex hypoplasia_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0011360IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• kyphosis_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0000160IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• hypoactivity_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0001402IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• increased circulating parathyroid hormone level_Kl<tm1.1Tel>/Kl<tm1.1Tel>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0002904IC57BL6ICRKltm11TelKltm11TelTgCdh16cre91Igr0TgCdh16cre91IgrKltm11Tel
• increased circulating phosphate level_Kl<tm1.1Tel>/Kl<tm1.1Tel>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0001566IC57BL6ICRKltm11TelKltm11TelTgCdh16cre91Igr0TgCdh16cre91IgrKltm11Tel
• small kidney_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0002989IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• decreased circulating parathyroid hormone level_Kl<tm1.1Tel>/Kl<tm1.1Tel>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0002905IC57BL6ICRKltm11TelKltm11TelTgCdh16cre91Igr0TgCdh16cre91IgrKltm11Tel
• nephrocalcinosis_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0003197IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• postnatal growth retardation_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0001732IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• premature death_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0002083IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• decreased body size_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0001265IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• abnormal kidney morphology_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0002135IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• renal fibrosis_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0003985IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• increased urine calcium level_Kl<tm1.1Tel>/Kl<tm1.1Tel>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0005441IC57BL6ICRKltm11TelKltm11TelTgCdh16cre91Igr0TgCdh16cre91IgrKltm11Tel
• increased circulating calcium level_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0000194IC57BL6FVBNKltm12TelKltm12TelKltm12Tel
• increased circulating phosphate level_Kl<tm1.2Tel>/Kl<tm1.2Tel>
  http://metadb.riken.jp/0001566IC57BL6FVBNKltm12TelKltm12TelKltm12Tel