Sandrine. Sander, et.al., Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis., Cancer cell, 2012, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/22897848

Sandrine. Sander, et.al., Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis., Cancer cell, 2012, 22

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased germinal center B cell number_Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>/Gt(ROSA)26Sor<tm13(CAG-MYC,-CD2*)Rsky>,Ighg1<tm1(cre)Cgn>/Ighg1<+>
  http://metadb.riken.jp/0008177I129P2OlaHsdC57BL6GtROSA26Sortm7Pik3caEGFPRskyGtROSA26Sortm13CAGMYCCD2RskyIghg1tm1creCgnIghg1GtROSA26Sortm7Pik3caEGFPRskyIghg1tm1creCgnGtROSA26Sortm13CAGMYCCD2RskyIghg1
• increased B cell derived lymphoma incidence_Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>/Gt(ROSA)26Sor<tm13(CAG-MYC,-CD2*)Rsky>,Ighg1<tm1(cre)Cgn>/Ighg1<+>
  http://metadb.riken.jp/0002023I129P2OlaHsdC57BL6GtROSA26Sortm7Pik3caEGFPRskyGtROSA26Sortm13CAGMYCCD2RskyIghg1tm1creCgnIghg1GtROSA26Sortm7Pik3caEGFPRskyIghg1tm1creCgnGtROSA26Sortm13CAGMYCCD2RskyIghg1
• abnormal class switch recombination_Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>/Gt(ROSA)26Sor<tm13(CAG-MYC,-CD2*)Rsky>,Ighg1<tm1(cre)Cgn>/Ighg1<+>
  http://metadb.riken.jp/0004816I129P2OlaHsdC57BL6GtROSA26Sortm7Pik3caEGFPRskyGtROSA26Sortm13CAGMYCCD2RskyIghg1tm1creCgnIghg1GtROSA26Sortm7Pik3caEGFPRskyIghg1tm1creCgnGtROSA26Sortm13CAGMYCCD2RskyIghg1
• premature death_Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>/Gt(ROSA)26Sor<tm13(CAG-MYC,-CD2*)Rsky>,Ighg1<tm1(cre)Cgn>/Ighg1<+>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6GtROSA26Sortm7Pik3caEGFPRskyGtROSA26Sortm13CAGMYCCD2RskyIghg1tm1creCgnIghg1GtROSA26Sortm7Pik3caEGFPRskyIghg1tm1creCgnGtROSA26Sortm13CAGMYCCD2RskyIghg1