Christine M. Sestero, et.al., CD5-dependent CK2 activation pathway regulates threshold for T cell anergy., Journal of immunology (Baltimore, Md. : 1950), 2012, 189

http://rdf.ncbi.nlm.nih.gov/pubmed/22904299

Christine M. Sestero, et.al., CD5-dependent CK2 activation pathway regulates threshold for T cell anergy., Journal of immunology (Baltimore, Md. : 1950), 2012, 189

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cd5<tm1.1Chra>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5447646

class

http://purl.org/net/cito/citesAsAuthority

• Cd5<tm1.1Chra>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5447646

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased interferon-gamma secretion_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008567IC57BL6FVBNCd5tm11ChraCd5tm11ChraTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchCd5tm11Chra
• decreased interferon-gamma secretion_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008567I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• increased interferon-gamma secretion_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008566IC57BL6FVBNCd5tm11ChraCd5tm11ChraTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchCd5tm11Chra
• decreased double-positive T cell number_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0005092IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• increased T cell proliferation_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0005348I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased T cell proliferation_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0005095IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• increased double-negative T cell number_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0005090IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• decreased T cell proliferation_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0005095I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• abnormal T cell anergy_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0008747IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• decreased interleukin-10 secretion_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008661I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased T-helper 17 cell number_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0010220IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• increased interleukin-6 secretion_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008705IC57BL6FVBNCd5tm11ChraCd5tm11ChraTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchCd5tm11Chra
• increased T cell apoptosis_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0006413I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased susceptibility to experimental autoimmune encephalomyelitis_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0004800IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• decreased CD4-positive, alpha beta T cell number_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0008075IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• increased interferon-gamma secretion_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008566I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased follicular B cell number_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0008174IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• abnormal T-helper 1 cell number_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008085I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• increased interleukin-6 secretion_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008705I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased T cell proliferation_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0005095IC57BL6FVBNCd5tm11ChraCd5tm11ChraTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchCd5tm11Chra
• decreased T-helper 17 cell number_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0010220I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased T-helper 2 cell number_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008091I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• increased interleukin-17 secretion_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008681I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased interleukin-2 secretion_Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008688I129P2OlaHsdC57BL6TgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21Kuch
• decreased susceptibility to experimental autoimmune encephalomyelitis_Cd5<tm1Cgn>/Cd5<tm1Cgn>
  http://metadb.riken.jp/0004800B6129P2Cd5tm1CgnCd5tm1CgnCd5tm1CgnCd5tm1Cgn
• increased T cell proliferation_Cd5<tm1Cgn>/Cd5<tm1Cgn>
  http://metadb.riken.jp/0005348B6129P2Cd5tm1CgnCd5tm1CgnCd5tm1CgnCd5tm1Cgn
• increased interleukin-17 secretion_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008681IC57BL6FVBNCd5tm11ChraCd5tm11ChraTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchCd5tm11Chra
• decreased T helper 1 cell number_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008087IC57BL6FVBNCd5tm11ChraCd5tm11ChraTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchCd5tm11Chra
• decreased interleukin-2 secretion_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0008688IC57BL6FVBNCd5tm11ChraCd5tm11ChraTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchCd5tm11Chra
• abnormal T cell physiology_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0002444IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• abnormal T cell anergy_Cd5<tm1Cgn>/Cd5<tm1Cgn>
  http://metadb.riken.jp/0008747B6129P2Cd5tm1CgnCd5tm1CgnCd5tm1CgnCd5tm1Cgn
• increased T cell proliferation_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0005348IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra
• increased regulatory T cell number_Cd5<tm1Cgn>/Cd5<tm1Cgn>
  http://metadb.riken.jp/0004973B6129P2Cd5tm1CgnCd5tm1CgnCd5tm1CgnCd5tm1Cgn
• decreased B cell number_Cd5<tm1.1Chra>/Cd5<tm1.1Chra>
  http://metadb.riken.jp/0005017IC57BL6FVBNCd5tm11ChraCd5tm11ChraCd5tm11Chra